Results 91 to 100 of about 7,134 (210)
Histological and mucoadhesion studies on transpalatal mucoadhesive disks of Rosiglitazone maleate [PDF]
, 2011 The present research is aimed to develop a mucoadhesive drug delivery system exhibiting a unique combination of mucoadhesion and controlled drug release in systemic manner to prolong residence in the soft palatal mucosa using rosiglitazone maleate as a ...
Madhav, N.V. Satheesh; Faculty of pharmacy, Integral university Basha Dashauli Kursi Road lucknow 226026, India. +2 more
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Impact of variables on buccal mucoadhesive film-forming spray for clotrimazole
Journal of Advanced Pharmaceutical Technology & ResearchBuccal spray is an attractive dosage form for its ease of application, especially for infant and geriatric patients. The aim in this work was to optimize and prepare a clotrimazole buccal spray through exploring the role of main variables producing a ...
Nidhal Khazaal Maraie +1 more
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ALKÜ Fen Bilimleri DergisiMucoadhesive polymers have the special functions which lead to adhesion to the mucin/ epithelial surface on the mucus-covered areas in the body such as eye, nose, vaginal and buccal cavities, and GI tract. Therefore, they provide to increase the residence time of the dosage form on the mucosa and to significantly improve the drug administration ...
Emine Büşra Eker Fidan +2 more
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, 2007 The study is focused on the evaluation of the potential bioadhesive behaviour of chitosan and thiolated chitosan (chitosan-TBA)- coated poly(isobutyl cyanoacrylates) (PIBCA) nanoparticles.
FARABOLLINI A. +4 more
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, 2019 Ying Xu,1 Shengzhe Lu,1 Qi Liu,2 Yun Hong,3 Bohui Xu,4 Qineng Ping,5 Xuefeng Jin,5 Yan Shen,5 Thomas J Webster,6 Yuefeng Rao3,7 1Department of Pharmaceutics, School of Pharmacy, Jiangsu University, Zhenjiang, 212013, China; 2Department of Dermatology ...
Jin X +9 more
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Chitosan-coated solid lipid nanoparticles for nose-to-brain drug delivery: A comprehensive review
Journal of Applied Pharmaceutical ResearchBackground: The blood-brain barrier (BBB) limits the effectiveness of treatment of several central nervous system (CNS) diseases, including Alzheimer's disease, Parkinson's disease, schizophrenia, and bipolar disorder.
Samruddhi Rakshe +4 more
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Assessment of mucoadhesion using small deformation rheology revisited
, 2017 This work revisits the commonly usedapproach to assess mucoadhesion in drug delivery by small deformation rheology. The results show that biosimilar mucus serves as a more predictive mucus model system when compared to mucin suspensions.
Harloff-Helleberg, Stine +2 more
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PharmaceuticsBackground/Objectives: This study aimed to develop and formulation-design curcumin-loaded buccal films using a green deep eutectic solvent (DES) to improve drug solubility and support localized mucosal delivery, with the help of a Design of Experiments ...
Melike Zeynep Ünükür Sevim +4 more
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Frontiers in MedicineIntravesical administration is a standard application route for the treatment of non-muscle-invasive bladder cancer, as it allows for high drug concentrations near tumor sites while largely avoiding systemic exposure and associated adverse effects ...
Hatixhe Sahini +3 more
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, 2020 Mucoadhesion is defined as the adhesion between a mucosal surface and, natural or synthetic, macromolecules. Mucoadhesion is a complex mechanism and it depends intermolecular interactions. The adhesive macromolecules can be part of a pharmaceutical formulation, turning it in a mucoadhesive preparation as well. The mucoadhesion mechanism is divided into
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