Results 81 to 90 of about 7,134 (210)
Mucoadhesion and mucosa-mimetic materials - a mini-review [PDF]
, 2015 Mucoadhesion describes an attractive interaction between dosage form and mucosal membrane. The evaluation of mucoadhesive excipients often requires the use of ex vivo mucosal tissues taken from laboratory animals. These can be difficult to source, highly
Khutoryanskiy, Vitaliy V. +1 more
core +1 more source
Eel skin as a model substrate for mucoadhesion studies
, 1997 The inherent fragility and instability of mammalian excised mucosal tissues constitutes a serious problem in ex vivo mucoadhesion studies. The present investigation was undertaken to assess the validity of eel (Anguilla anguilla) skin as a model mucous ...
Bernicchi R +4 more
core
Oral Textural Properties of Easy-to-swallow Foods
Chemical Engineering TransactionsThis study is part of a broader project aimed at designing foods tailored to specific populations, such as easy-to-swallow products for individuals with dysphagia, emphasizing the need for a deeper understanding into oral processing and its physiological
Giorgio Innocenzo Ascrizzi, Laura Piazza
doaj
BIO-PROTOCOLIntravesical instillation is an efficient therapeutic technique based on targeted administration of a drug directly into the lesion for the treatment of bladder diseases. This is an alternative to traditional systemic administration of drugs. However, this technique requires repeated procedures, which can lead to even greater inflammation and infection
Maria Saveleva +2 more
openaire +3 more sources
New insights into the mucoadhesion of pectins by AFM roughness parameters in combination with SPR [PDF]
, 2011 The object of this study was to assess the mucoadhesion of the three main commercially available types of pectin by atomic force microscopy (AFM) and surface Plasmon resonance (SPR).
Beate Klösgen +9 more
core +1 more source
Designing of the mucoadhesive intravaginal spermicidal films
Indian Journal of Pharmaceutical Sciences, 2010 A mucoadhesive drug delivery system for local delivery of metronidazole through vaginal route was formulated. Films were prepared by solvent evaporation method using various compositions of Carbopol, hydroxypropylmethylcellulose, chitosan, Polyox and propylene glycol.
Kawarkhe, Shilpa, Poddar, S. S.
openaire +3 more sources
Drug Delivery, 2019 Oral drug delivery is an attractive noninvasive alternative to injectables. However, oral delivery of biopharmaceuticals is highly challenging due to low stability during transit in the gastrointestinal tract (GIT), resulting in low systemic ...
Stine Harloff-Helleberg +6 more
doaj +1 more source
Chitosan strips with controlled micro-porosity to improve buccal mucoadhesion
, 2014 Objectives: Here, we propose the application of a novel film-like chitosan (CH) strips as oral patches to enhance wound healing and buccal drug delivery.
G. Lodi +7 more
core +1 more source
Advanced Science, 2018 Initially, chemotherapy is effective for treatment of bladder cancer after transurethral resection of the bladder. However, certain patients progressively become unresponsive after multiple treatment cycles, which results from the rapid and almost ...
Hui Guo +7 more
doaj +1 more source
Pullulan-Based Spray-Dried Mucoadhesive Microparticles for Sustained Oromucosal Drug Delivery
PharmaceuticsMucoadhesive microparticles for oromucosal drug delivery offer several advantages, including intimate contact with the mucosa, delivery to less accessible regions, extended residence time, sustained drug release, reduced irritation, and improved patient ...
Ting Liu +4 more
doaj +1 more source