Results 111 to 120 of about 9,290 (251)

Nicotine stabilization in composite sodium alginate based wafers and films for nicotine replacement therapy [PDF]

, 2017
Composite wafers and films comprising HPMC and sodium alginate (SA) were formulated for nicotine (NIC) replacement therapy via the buccal route. Magnesium aluminium silicate (MAS) was added in different concentration ratios (0.25, 0.5, 0.75) to stabilize
Adhikari, Adrian, Aguzzi, Benowitz, Boateng, Boateng, Boateng, Dash, Gilman, Joshua S. Boateng, Khan, Manivannan, Mihranyan, Morales, Nair, Nair, Obinna C. Okeke, Okeke, Pandey, Pavlidou, Pawar, Pongjanyakul, Pongjanyakul, Pongjanyakul, Prabaharan, RakiĿ, Rowe, Sattar, Shoaib, Siepmann, Singhvi, Smart, ÿkinci   +32 more
core   +1 more source

Substantive Dimethicone-Based Mucoadhesive Coatings

Materials
It is challenging to deliver therapeutics in the oral environment due to the wet surfaces, the nature of the mucosa and the potential for saliva washout. In this study, the development of a mucoadhesive dimethicone-based oral carrier system for adhesion to the hard tissue and mucosa in the mouth was examined.
Miller, Sophie, Omoto, Nicole, DeCamp, Ryan, Gloeb, Gavin, Gross, Stephen M.   +4 more
openaire   +2 more sources

Bioadhesive properties of Gantrez nanoparticles [PDF]

, 2005
Bioadhesive nanoparticles have been proposed as carriers for the oral delivery of poorly available drugs and facilitate the use of this route.
Arbos, P. (P.), Campanero, M.A. (Miguel Angel), Espuelas, S. (Socorro), Huici, M. (M.), Irache, J.M. (Juan Manuel), Konecny, M. (Mónica)   +5 more
core  

Maleimide-bearing nanogels as novel mucoadhesive materials for drug delivery [PDF]

, 2016
Novel maleimide-functionalised nanogels have been synthesised via the polymerisation of 2,5-dimethylfuran-protected 3-maleimidoethyl butylacrylate in the presence of presynthesised poly(N-vinylpyrrolidone) (PVP) nanogel scaffolds using surfactant-free ...
Andrews, Bernkop-Schnurch, Bernkop-Schnürch, Boddupalli, Chacko, Cook, Davidovich-Pinhas, Davidovich-Pinhas, Ellman, Fontaine, Hasegawa, Hayashi, Irmukhametova, Kao, Khutoryanskiy, Khutoryanskiy, Li, Li, Lowe, Ludwig, Mantovani, Maya, Molina, Morales, Nair, Northrop, Peppas, Prosperi-Porta, Schmitz, Shaikh, Singhvi, Sosnik, Storha, Syrett, Valenta, Wagh, Xu, Yang   +37 more
core   +1 more source

Gellan gum-based mucoadhesive microspheres of almotriptan for nasal administration: Formulation optimization using factorial design, characterization, and in vitro evaluation

Journal of Pharmacy and Bioallied Sciences, 2014
Background: Almotriptan malate (ALM), indicated for the treatment of migraine in adults is not a drug candidate feasible to be administered through the oral route during the attack due to its associated symptoms such as nausea and vomiting. This obviates
Zaheer Abbas, Sachin Marihal
doaj   +1 more source

Aldehyde-functional thermoresponsive diblock copolymer worm gels exhibit strong mucoadhesion

, 2022
Emma E. Brotherton, Thomas J. Neal, Daulet B. Kaldybekov, Mark J. Smallridge, Vitaliy V. Khutoryanskiy, Steven P. Armes   +5 more
openalex   +2 more sources

Synthesis of thiolated, PEGylated and POZylated silica nanoparticles and evaluation of their retention on rat intestinal mucosa in vitro [PDF]

, 2018
In this study, we synthesised thiolated silica nanoparticles using 3-mercaptopropyltrimethoxysilane and functionalised them with either 5 kDa methoxy polyethylene glycol maleimide (PEG) or 5 kDa alkyne-terminated poly(2-ethyl-2-oxazoline) (POZ). The main
Khutoryanskiy, Vitaliy V., Lau, Wing Man, Ng, Keng Wooi, Ways, Twana Mohammed M.   +3 more
core   +1 more source

Synthesis and Characterization of a Cationic Thiomer Based on Ethyl Cellulose for Realization of Mucoadhesive Tablets and Nanoparticles

International Journal of Nanomedicine, 2022
Deni Rahmat, Clairine Devina Faculty of Pharmacy, Pancasila University, Srengseng Sawah, Jagakarsa, South Jakarta, 12640, IndonesiaCorrespondence: Deni Rahmat, Faculty of Pharmacy, Pancasila University, Srengseng Sawah, Jagakarsa, South Jakarta, 12640 ...
Rahmat D, Devina C
doaj  

Probing the mucoadhesive interactions between porcine gastric mucin and some water-soluble polymers [PDF]

, 2015
This study investigates the structural features of porcine gastric mucin (PGM) in aqueous dispersions and its interactions with water-soluble polymers (poly(acrylic acid) (PAA), poly(methacrylic acid) (PMAA), poly(ethylene oxide), and poly(ethylene ...
Albarkah, Yasser R., Green, R. J., Khutoryanskiy, Vitaliy V.   +2 more
core   +1 more source

Oral Textural Properties of Easy-to-swallow Foods

Chemical Engineering Transactions
This study is part of a broader project aimed at designing foods tailored to specific populations, such as easy-to-swallow products for individuals with dysphagia, emphasizing the need for a deeper understanding into oral processing and its physiological
Giorgio Innocenzo Ascrizzi, Laura Piazza
doaj