Results 51 to 60 of about 9,290 (251)

Improved Mucoadhesion, Permeation and In Vitro Anticancer Potential of Synthesized Thiolated Acacia and Karaya Gum Combination: A Systematic Study

Molecules, 2022
Thiolation of polymers is one of the most appropriate approaches to impart higher mechanical strength and mucoadhesion. Thiol modification of gum karaya and gum acacia was carried out by esterification with 80% thioglycolic acid.
Neha Munot, Ujjwala Kandekar, Chaitali Rikame, Abhinandan Patil, Poulomi Sengupta, Shabana Urooj, Anusha Bilal   +6 more
doaj   +1 more source

Lyophilized wafers comprising carrageenan and pluronic acid for buccal drug delivery using model soluble and insoluble drugs [PDF]

, 2013
Lyophilized muco-adhesive wafers with optimum drug loading for potential buccal delivery have been developed. A freeze-annealing cycle was used to obtain optimized wafers from aqueous gels containing 2% κ-carrageenan (CAR 911), 4% pluronic acid (F127), 4.
Babur Chowdhry, Balji, Bansal, Boateng, Boateng, De Brabander, Dixit, Eliasson, Farnoosh Kianfar, Joshua S. Boateng, Kianfar, Kianfar, Kianfar, Kianfar, Lin, Luppi, Mathias, Matthews, McGinnity, Milan Antonijevic, Narasimhan, Passerini, Pyne, Ritger, Roy, Ruiz, Schneid, Shaikh, Siepmann, Smart, Tsinontides, Wu   +31 more
core   +1 more source

Formulation and evaluation of controlled release matrix mucoadhesive tablets of domperidone using Salvia plebeian gum

Journal of Advanced Pharmaceutical Technology & Research, 2011
The aim of study was to prepare controlled release matrix mucoadhesive tablets of domperidone using Salvia plebeian gum as natural polymer. Tablets were formulated by direct compression technology employing the natural polymer in different concentrations
Gurpreet Arora, Karan Malik, Inderbir Singh, Sandeep Arora, Vikas Rana   +4 more
doaj   +1 more source

Development of Thermosensitive and Mucoadhesive Hydrogel for Buccal Delivery of (S)-Ketamine

Pharmaceutics, 2022
(S)-ketamine presents potential for the management of acute pain and, more specifically, for the prevention of pain associated with care. However, the administration route can be a source of pain and distress.
Agathe Thouvenin, Balthazar Toussaint, Jelena Marinovic, Anne-Laure Gilles, Amélie Dufaÿ Wojcicki, Vincent Boudy   +5 more
doaj   +1 more source

Mucoadhesive maleimide-functionalised liposomes for drug delivery to urinary bladder [PDF]

, 2018
Intravesical drug administration is used to deliver chemotherapeutic agents via a catheter to treat bladder cancer. The major limitation of this treatment is poor retention of the drug in the bladder due to periodic urine voiding. In this work, maleimide-
Kaldybekov, Daulet, Khutoryanskiy, Vitaliy V., Opanasopit, Praneet, Tonglairoum, Prasopchai   +3 more
core   +1 more source

Buccal Thin Films as Potent Permeation Enhancers for Cytisine Transbuccal Delivery

Membranes, 2022
Cytisine (CYT) is a powerful anti-smoking compound which could greatly benefit from transbuccal delivery because of both its unfavorable pharmacokinetics after oral administration and its intrinsic ability to permeate the buccal mucosa. This work aims to
Viviana De Caro, Giuseppe Angellotti, Fabio D’Agostino, Giulia Di Prima   +3 more
doaj   +1 more source

Development of Eudragit^® Nanoparticles for Intranasal Drug Delivery: Preliminary Technological and Toxicological Evaluation

Applied Sciences, 2022
Intranasal administration has assumed in the last years an increasing value as an alternative strategy for the systemic adsorption of drugs, as an alternative to oral and parenteral routes thanks to the high vascularized nasal mucosa.
Roberta Corsaro, Rosamaria Lombardo, Carla Ghelardini, Lorenzo Di Cesare Mannelli, Daniele Bani, Angela Bonaccorso, Rosario Pignatello   +6 more
doaj   +1 more source

Mucoadhesion and mucosa-mimetic materials - a mini-review [PDF]

, 2015
Mucoadhesion describes an attractive interaction between dosage form and mucosal membrane. The evaluation of mucoadhesive excipients often requires the use of ex vivo mucosal tissues taken from laboratory animals. These can be difficult to source, highly
Cook, Michael T., Khutoryanskiy, Vitaliy V.   +1 more
core   +1 more source

The Vaginal-PVPA: A Vaginal Mucosa-Mimicking In Vitro Permeation Tool for Evaluation of Mucoadhesive Formulations

Pharmaceutics, 2020
Drug administration to the vaginal site has gained increasing attention in past decades, highlighting the need for reliable in vitro methods to assess the performance of novel formulations.
Margherita Falavigna, Martina Pattacini, Richard Wibel, Fabio Sonvico, Natasa Škalko-Basnet, Gøril Eide Flaten   +5 more
doaj   +1 more source

Composite alginate and gelatin based bio-polymeric wafers containing silver sulfadiazine for wound healing [PDF]

, 2015
Lyophilized wafers comprising sodium alginate (SA) and gelatin (GE) (0/100, 75/25, 50/50, 25/75, 0/100 SA/GE, respectively) with silver sulfadiazine (SSD, 0.1% w/w) have been developed for potential application on infected chronic wounds.
Asane, Atiyeh, Ayensu, Aziz, Balakrishnam, Boanini, Boateng, Boateng, Boateng, Carter, Choi, Devi, Dong, Fajardo, Goh, Harshavardhan Pawar, Howard, Jiang, Joshua Boateng, Kuijpers, Li, Liu, Mogoşanua, Moura, Obinna Okeke, Panouille, Pawar, Pawar, Pereira, Rocio Burgos-Amador, Roy, Roy, Saarai, Saarai, Salamat-Miller, Singh, Thomas, Watson   +37 more
core   +1 more source