Results 81 to 90 of about 434,754 (278)

Female‐Specific Risk of TAS2R Variants in Chronic Rhinosinusitis: A Hospital‐Based Cohort Study From the Taiwan Precision Medicine Initiative

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Bitter taste receptors (T2Rs) function in the innate immune defense of the sinonasal mucosa; however, the genetic association between the TAS2R gene family and chronic rhinosinusitis (CRS) remains understudied in Asian populations.
Rong‐San Jiang, Man‐Wei Hua, I‐Chieh Chen, Yi‐Ming Chen, Shun‐Hung Lin, Kuan‐Yu Lai, Yi‐Chen Chen   +6 more
wiley   +1 more source

Effect of needle puncture and electro-acupuncture on mucociliary clearance in anesthetized quails

BMC Complementary and Alternative Medicine, 2006
Background Acupuncture therapy for obstructive respiratory diseases has been effectively used in clinical practice and the acupuncture points or acupoints of Zhongfu and Tiantu are commonly-used acupoints to treat patients with the diseases.
Wang Tianshan, Xutian Stevenson, Sun Feng, Wang Jiulin, Tai Shusheng, King Malcolm   +5 more
doaj   +1 more source

Influence of Intranasal Drugs on Human Nasal Mucociliary Clearance and Ciliary Beat Frequency

Allergy Asthma and Immunology Research, 2018
The nasal mucociliary clearance system, which comprises epithelial cilia and mucus from goblet cells, is an important intrinsic defense mechanism of the upper respiratory tract.
J. Jiao, Luo Zhang
semanticscholar   +1 more source

Overcoming intranasal delivery barriers with ultrastable polyzwitterionic siRNA nanocages for enhanced glioblastoma therapy

BMEMat, EarlyView.
A ROS‐responsive, zwitterionic nanocage enables stable, intranasal siRNA delivery to glioblastoma, promoting deep tumor penetration via non‐degradative pathways and trigeminal nerve transport. This platform achieves durable gene silencing and tumor suppression, offering a non‐invasive, storage‐stable strategy for treating glioma and other neurological ...
Jingwen Xie, Jingxing Si, Xiaobei Deng, Jing Tan, Ruijie Zhu, Jizhou Qi, Gaoxia Ma, Bin Wang, Yi Wang, Yunzhou Guo, Yuping Chen, Shiqun Shao, Youqing Shen   +12 more
wiley   +1 more source

A novel two-step sequential bioaccessibility test for potentially toxic elements in inhaled particulate matter transported into the gastrointestinal tract by mucociliary clearance [PDF]

, 2017
A novel two-step sequential extraction has been developed to assess the bioaccessibility of As, Cd, Cr, Cu, Fe, Mn, Ni, Pb, and Zn in airborne particulate matter following inhalation and transport into the human gastrointestinal tract by mucociliary ...
Alpofead, Jawad Ali Hussein, Davidson, Christine M., Littlejohn, David   +2 more
core   +1 more source

PDCD5 Contributes to Airway Epithelial Cell Damage via Mitochondrial Pathway and Participates in COPD Pathogenesis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Airway epithelial injury plays a critical role in the pathogenesis of chronic obstructive pulmonary disease (COPD). Mitochondrial dysfunction is implicated in this injury, while the underlying mechanism remains incompletely understood. RNA sequencing was conducted to identify key genes involved in mitochondrial dysfunction in airway epithelial
Hu Shan, Rui Zhang, Yu‐er Li, Rui Li, Shao‐bo Ge, Jin Liu, Shi‐yuan Yao, Xia Yang, Tao Zhang, Ming Zhang   +9 more
wiley   +1 more source

Regulation of mucociliary clearance in health and disease [PDF]

European Respiratory Journal, 1999
Airway secretions are cleared by mucociliary clearance (MCC), in addition to other mechanisms such as cough, peristalsis, two-phase gas-liquid flow and alveolar clearance. MCC comprises the cephalad movement of mucus caused by the cilia lining the conducting airways until it can be swallowed or expectorated.
E, Houtmeyers, R, Gosselink, G, Gayan-Ramirez, M, Decramer   +3 more
openaire   +2 more sources

Cilia beating misalignment, immotility or death pathologically affect the efficiency of mucus-clearance

Communications Physics
To perform mucociliary clearance, motile cilia covering the surface of the respiratory tract coordinate their beating motions to push mucus out of the upper airways.
Émeline Laborie, Simone Melchionna, Fabio Sterpone   +2 more
doaj   +1 more source

Batuk Kronik pada Anak: masalah dan tata laksana

Sari Pediatri, 2016
Batuk kronik pada anak cukup banyak dijumpai dalam praktek sehari-hari. Pada pasien anak, gejala batuk yang kronik atau berulang dapat mengganggu aktivitas sehari-hari, mengurangi nafsu makan, dan pada akhirnya dapat mengganggu proses tumbuh kembang ...
Darmawan B Setyanto
doaj   +1 more source

Acute and chronic in vivo effects of exposure to nicotine and propylene glycol from an E-cigarette on mucociliary clearance in a murine model

Inhalation Toxicology, 2017
Objective: To determine the effect of an acute (1 week) and chronic (3 weeks) exposure to E-cigarette (E-cig) emissions on mucociliary clearance (MCC) in murine lungs.
B. Laube, Nima Afshar-Mohajer, K. Koehler, Gang Chen, P. Lazarus, J. Collaco, S. McGrath-Morrow   +6 more
semanticscholar   +1 more source