Results 91 to 100 of about 654,486 (255)

Lack of GAS2L2 Causes PCD by Impairing Cilia Orientation and Mucociliary Clearance.

American Journal of Human Genetics, 2019
Primary ciliary dyskinesia (PCD) is a genetic disorder in which impaired ciliary function leads to chronic airway disease. Exome sequencing of a PCD subject identified an apparent homozygous frameshift variant, c.887_890delTAAG (p.Val296Glyfs∗13), in ...
Ximena M. Bustamante-Marin, W. Yin, P. Sears, Michael E Werner, Eva J Brotslaw, B. Mitchell, C. Jania, K. Zeman, T. D. Rogers, Laura E. Herring, L. Réfabert, Lucie Thomas, S. Amselem, E. Escudier, M. Legendre, B. R. Grubb, M. Knowles, M. Zariwala, L. Ostrowski   +18 more
semanticscholar   +1 more source

Clinical Management and Outcomes of Neonatal Rhinitis Nasal Obstruction: A Scoping Review

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective Neonatal rhinitis represents an underdiagnosed yet potentially serious condition in newborns. Standardized diagnostic and treatment protocols remain lacking. The objective is to review the current literature on the etiology, diagnosis, and management of neonatal rhinitis in infants ≤8 months of age.
Anthony Victor, Mathieu Bergeron
wiley   +1 more source

Investigation of the tracheal mucociliary clearance in snakes with and without boid inclusion body disease and lung pathology [PDF]

, 2018
Pneumonia is a common complication of boid inclusion body disease (BIBD) in snakes. The tracheal mucociliary apparatus of eight boas (Boa constrictor) and two pythons (Python regius, Morelia viridis) was examined to assess whether absent or reduced ...
Wyss, Fabia, Udo Hetzel, Martin Frenz, Jean-Michel Hatt, Saskia Keller, Hatt, Jean-Michel, Jaroslav Rička, Schneiter, Martin, Keller, Saskia, Rička, Jaroslav, Fabia Wyss, Martin Schneiter, FTA Pathologie, Frenz, Martin, Hatt, Jean-Michel; https://orcid.org/, Hetzel, Udo, Pathologie, FTA   +16 more
core   +1 more source

Measurements of mucociliary clearance and small molecule absorption for researching airways disease

, 2018
Measurements of mucociliary clearance and small molecule absorption for researching airways ...
Tim Corcoran (13065069), Ashok Muthukrishnan (15818204)   +1 more
core   +1 more source

Effect of ivacaftor on mucociliary clearance and clinical outcomes in cystic fibrosis patients with G551D-CFTR.

JCI Insight, 2018
BACKGROUND The ability to restore cystic fibrosis transmembrane regulator (CFTR) function with effective small molecule modulators in patients with cystic fibrosis provides an opportunity to study relationships between CFTR ion channel function, organ ...
S. Donaldson, B. Laube, T. Corcoran, P. Bhambhvani, K. Zeman, Agathe S. Ceppe, P. Zeitlin, P. Mogayzel, M. Boyle, L. Locke, M. Myerburg, J. Pilewski, Brian Flanagan, S. Rowe, W. Bennett   +14 more
semanticscholar   +1 more source

Cell‐Based Micro/Nanorobots: From Living Carriers to Living Therapeutic Specialists

SmartBot, EarlyView.
Cell‐based micro/nanorobots integrate evolutionarily acquired biological intelligence with engineered capabilities, offering new opportunities for precision medicine in vivo. However, the complex physiological environments of different organs pose significant challenges to their clinical translation.
Junfeng Wu, Zhaoyu Zhang, Ke Xu, Enkuo Li, Yuting Cui, Yuting Zhou, Huanyu Zhou, Beipei Zhang, Shuai Jiang, Xiaodong Wang, Jialin Jiang, Lianqing Liu, Niandong Jiao   +12 more
wiley   +1 more source

Cilia beating misalignment, immotility or death pathologically affect the efficiency of mucus-clearance

Communications Physics
To perform mucociliary clearance, motile cilia covering the surface of the respiratory tract coordinate their beating motions to push mucus out of the upper airways.
Émeline Laborie, Simone Melchionna, Fabio Sterpone   +2 more
doaj   +1 more source

Batuk Kronik pada Anak: masalah dan tata laksana

Sari Pediatri, 2016
Batuk kronik pada anak cukup banyak dijumpai dalam praktek sehari-hari. Pada pasien anak, gejala batuk yang kronik atau berulang dapat mengganggu aktivitas sehari-hari, mengurangi nafsu makan, dan pada akhirnya dapat mengganggu proses tumbuh kembang ...
Darmawan B Setyanto
doaj   +1 more source

Influence of Intranasal Drugs on Human Nasal Mucociliary Clearance and Ciliary Beat Frequency

Allergy Asthma and Immunology Research, 2018
The nasal mucociliary clearance system, which comprises epithelial cilia and mucus from goblet cells, is an important intrinsic defense mechanism of the upper respiratory tract.
Jian Jiao, Luo Zhang
semanticscholar   +1 more source

Cation Enrichment and Hypersialylation in Chronic Rhinosinusitis Mucus

International Forum of Allergy &Rhinology, EarlyView.
Amanda M. Wood, Rachel E. Detwiler, McKenna Coughlin, Chelsea E. Pollard, Jeremiah A. Alt, Abigail Pulsipher, Jessica Kramer Stratton   +6 more
wiley   +1 more source