Results 81 to 90 of about 25,939 (244)

The Occurrence of Gene Fusions in Thyroid Lesions and the Relation With Chronic Lymphocytic Thyroiditis

Pathology International, Volume 76, Issue 1, January 2026.
We identified both known and novel gene fusions in thyroid neoplasia, including several previously reported only in nonthyroid malignancies. Gene fusion–positive tumors were significantly (p < 0.001, annotated as ***) associated with florid chronic lymphocytic thyroiditis, unlike tumors driven by somatic mutations or copy number variations.
Maaia Margo Jentus, Tom van Wezel, Dina Ruano, Marieke Snel, Abbey Schepers, Stijn Crobach, Hans Morreau   +6 more
wiley   +1 more source

Nasopharyngeal mucoepidermoid carcinoma with mastermind-like transcriptional coactivator 2 translocation: A case report and comprehensive literature review of a rare entity

SAGE Open Medical Case Reports
Mucoepidermoid carcinoma is one of the most common malignant tumors in salivary glands and is usually associated with mastermind-like transcriptional coactivator 2 (MAML2) rearrangement.
Chan-Fong Chio, Wan-Pang Sam, Sio-In Wong, Cheong-Un Sio, Lai-Fong Kok, Ki-Man Pai, Thazin Hlaing   +6 more
doaj   +1 more source

Mucoepidermoid carcinoma of the base of tongue [PDF]

, 2011
Mucoepidermoid carcinomas are thought to arise from the reserve cells of salivary gland ducts. Minor salivary glands are located all around the oral cavity and base of the tongue; however few cases of MEC of the base of the tongue have been reported in ...
Ghaffar, Shehzad, Junaid, Montasir, Sobani, Zain-ul-Abedeen, Suhail, Anwar   +3 more
core   +1 more source

Genetic analyses of undifferentiated small round cell sarcoma identifies a novel sarcoma subtype with a recurrent CRTC1-SS18 gene fusion [PDF]

, 2018
In recent years, undifferentiated small round cell sarcomas (USRCSs) have been divided into a variety of new, rare, sarcoma subtypes, including the group of Ewing-like sarcomas, which have the morphological appearance of Ewing sarcomas, but carry CIC ...
Antonescu, Antonescu, Bray, Brohl, Cellier, Clark, Conkright, Dobin, Enlund, Ge, Haas, Iourgenko, Kawamura-Saito, Machado, Middeljans, Nielsen, Nordkvist, Pierron, Puls, R Development Core Team, Schram, Skytting, Specht, Sugita, Tirado, Tonon   +25 more
core   +3 more sources

MAML2‐Rearranged Hidradenoma of the Breast: Clinicopathologic and Molecular Analysis of Four Patients

Case Reports in Pathology, Volume 2026, Issue 1, 2026.
Hidradenoma (HA) is a rare, benign adnexal tumor typically arising in the skin, with only a few reported cases in the breast. Histologically, HA displays solid and cystic patterns with diverse cellular components. Although MAML2 gene rearrangement is observed in some cutaneous HAs, its significance in breast HA remains unclear.
Naomi Gondo, Yasuyo Ohi, Tsubasa Hiraki, Akira I. Hida, Shuichi Kanemitsu, Yasuaki Sagara, Shinji Ohno, Suraiya Saleem   +7 more
wiley   +1 more source

Central mucoepidermoid carcinoma of the mandible: a rare case report with diagnostic dilemma and review of the literature

The Egyptian Journal of Otolaryngology, 2016
En Abstract Introduction Primary central mucoepidermoid carcinoma of jaws is a rare lesion comprising 2–3% of all mucoepidermoid carcinomas reported in the literature. It affects the mandible as unilocular or multilocular radiographic lesions.
Praveer K. Banerjee, Abhineet Jain, Sonam Rathi   +2 more
doaj   +1 more source

AP2M1 Amplification Orchestrates Notch‐Mediated Chemoresistance in Hematopoietic Stem Cells of Acute Myeloid Leukemia Patients

Advanced Science, Volume 12, Issue 48, December 29, 2025.
The precise regulation of AP2M1 is essential for normal hematopoiesis. Overexpression of AP2M1 negatively affects the clinical outcomes of AML patients. Upregulation of AP2M1 enhances stemness and chemoresistance in HSPC cells of AML. AP2M1 modulates NOTCH1 expression, enhancing the Notch1 signaling pathway.
Hansong Lee, Eun Kyoung Kim, Hee Young Ju, Chae Rin Lee, Soyul Ahn, Eun‐Sun Kim, Kyungjae Myung, Won Kyu Kim, Su‐Yeon Cho, Yujin Kwon, Dokyoung Kim, Yeuni Yu, Eun Jung Kwon, Hyomin Kim, Seong Ik Mun, Dong Min Lim, Kihun Kim, Hye Jin Heo, Seung Eun Baek, Sun Young Lee, Hyunsoo Cho, Eun Young Choi, Tae Sik Goh, Ninib Baryawno, Dongjun Lee, Ki Sun Jung, Keon Hee Yoo, Chang‐Kyu Oh, Yun Hak Kim   +28 more
wiley   +1 more source

Docetaxel for High-Grade Mucoepidermoid Carcinoma of the Lung

Journal of Cancer Research and Practice, 2015
Mucoepidermoid carcinoma is considered to be one of the salivary gland-type cancers, which seldom originate from the lung. Herein, we report a 69-year-old female with primary pulmonary high-grade mucoepidermoid carcinoma.
Hui-Ching Wang, Shih-Feng Cho
doaj   +1 more source

Primary intraosseous carcinoma of mandible: an update on review of literature with a case report [PDF]

, 2010
Primary intraosseous carcinoma (PIOC) is a rare malignant neoplasm of the jaws which is locally aggressive with quite poor prognosis. Overall and disease free survival is poor with almost 50% patients failing within first 2 years of follow up and ...
Jindal, Sanjeev Kumar, Puri, Nidhi, Shambhulingappa, P., Sheikh, Soheyl   +3 more
core   +1 more source

Clinical Features and Differential Diagnoses in Laryngeal Mucoepidermoid Carcinoma

Clinical Medicine Insights: Pathology, 2012
Mucoepidermoid carcinoma is the most common malignant tumor of salivary glands. However, it is a rare entity in larynx. Laryngeal cases are frequently misdiagnosed with other malignancies and they are under-reported.
Sepideh Mokhtari, Saeedeh Mokhtari
doaj   +1 more source