Results 131 to 140 of about 2,851 (178)
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Paediatric Respiratory Reviews, 2007
Mucus accumulation in the lower airways is a key feature of cystic fibrosis (CF) lung disease. The major component of mucus in CF is not mucin derived from mucus producing cells but rather pus that includes viscous material such as polymerized DNA derived from degraded neutrophils. This has important implications for mucolytic therapy aiming to improve
Markus O Henke, Felix Ratjen
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Mucus accumulation in the lower airways is a key feature of cystic fibrosis (CF) lung disease. The major component of mucus in CF is not mucin derived from mucus producing cells but rather pus that includes viscous material such as polymerized DNA derived from degraded neutrophils. This has important implications for mucolytic therapy aiming to improve
Markus O Henke, Felix Ratjen
exaly +3 more sources
Mucolytics and antioxidant activity
Life Sciences, 1999We investigated effects of the mucolytics ambroxol and N-acetylcysteine on airways reactivity evoked by histamine in guinea pigs exposed to toluene vapors. We did not find significant changes in reactivity of tracheal smooth muscle from animals treated with mucolytics compared to the control group.
Sona Fraňová
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The role of mucolytics in COPD
Independent Nurse, 2006Patients with COPD may benefit from mucolytics. Rachel Booker explains the evidence and options
Rachel Booker
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New England Journal of Medicine, 1955
THE use of detergents in the liquefaction of thick mucoid and purulent exudates in the alveoli and bronchial tree was not practical until recent years, owing to the fact that no surfactant with appropriate properties was known. Agents that lower surface tension had long been used in suppurating wounds and body cavities.
M L, Tainter, F C, Nachod, J G, Bird
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THE use of detergents in the liquefaction of thick mucoid and purulent exudates in the alveoli and bronchial tree was not practical until recent years, owing to the fact that no surfactant with appropriate properties was known. Agents that lower surface tension had long been used in suppurating wounds and body cavities.
M L, Tainter, F C, Nachod, J G, Bird
openaire +2 more sources
Summary of the National Mucolytic Study
Chest, 1990The study was designed to assess the safety and efficacy of orally-administered iodinated glycerol (Organidin) in the management of patients with stable, chronic obstructive bronchitis, who complained of cough and difficulty in raising sputum, and who would be candidates for mucolytic-expectorant ...
E J, Morgan, T L, Petty
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Evaluation of a new mucolytic drug
Clinical Pharmacology & Therapeutics, 1974In a double‐blind crossover trial, the effect of a new mucolytic drug, the sodium salt of 2‐mercaptoethane sulfonic acid (Mistabron) (6 ml, 200 mg per milliliter) was compared with 0.9% sodium chloride (6 ml) over 16 consecutive days in 31 sub;ects with chronic bronchitis.
S N, Steen +3 more
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Mucolytics, Expectorants, and Mucokinetic Medications
Respiratory Care, 2007In health, the airways are lined by a layer of protective mucus gel that sits atop a watery periciliary fluid. Mucus is an adhesive, viscoelastic gel, the biophysical properties of which are largely determined by entanglements of long polymeric gel-forming mucins, MUC5AC and MUC5B.
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Pediatrics, 1953
Normal maternal serum and newborn infant serum have been compared with respect to their content of nonspecific hyaluronidase inhibitor and mucoprotein. Elevations in serum levels of hyaluronidase inhibitor and mucoprotein were found in maternal serum while decreased concentrations of mucoprotein and normal levels of hyaluronidase inhibitor ...
ROBERT A. GOOD +3 more
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Normal maternal serum and newborn infant serum have been compared with respect to their content of nonspecific hyaluronidase inhibitor and mucoprotein. Elevations in serum levels of hyaluronidase inhibitor and mucoprotein were found in maternal serum while decreased concentrations of mucoprotein and normal levels of hyaluronidase inhibitor ...
ROBERT A. GOOD +3 more
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Mucolytic and Mucokinetic Therapy
Pulmonary Pharmacology, 1996P J, Wills, P J, Cole
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