Results 251 to 260 of about 134,087 (293)

Interactions of commensal and pathogenic microorganisms with the intestinal mucosal barrier

open access: yesNature Reviews Microbiology, 2018
The intestinal mucosal barrier is composed of epithelial cells that are protected by an overlying host-secreted mucous layer and functions as the first line of defence against pathogenic and non-pathogenic microorganisms. Some microorganisms have evolved
Eric C Martens   +2 more
exaly   +2 more sources

The gastric mucosal barrier

Medical Journal of Australia, 1985
The 'gastric mucosal barrier' is a descriptive term for the ability of the gastric epithelium to hold a large (10(5)) H+ concentration gradient from lumen to mucosa under physiological conditions. Compounds which classically have been used to describe the functional integrity of the 'barrier', in addition to very low H+ diffusion from lumen to mucosa ...
openaire   +5 more sources

The pancreatic duct mucosal barrier

The American Journal of Surgery, 1979
The main pancreatic duct in cats possesses a relatively strong barrier to the diffusion of bicarbonate ions (HCO3-). We studied some of the characteristics of this barrier by perfusing the duct with a solution similar in composition to pancreatic juice before and after exposing the duct mucosa to various test agents. The difference in net flux of HCO3-
H A, Reber, C, Roberts, L W, Way
openaire   +2 more sources

The gastric mucosal barrier and ulceration

Brain Research Bulletin, 1980
The gastric mucosal barrier is that property which defends against acid and which impedes diffusion of acid from the lumen into the mucosa. The disappearance of luminal H+ is linearly related to luminal (H+) both in the normal stomach and in stomachs exposed to barrier breakers. The latter invaribaly produce anatomic evidence of surface cellular injury.
W, Silen, R, Schiessel, E, Kivilaakso
openaire   +2 more sources

Probiotics and mucosal barrier in children

Current Opinion in Clinical Nutrition & Metabolic Care, 2008
Colonization by the microbiota plays an important role in intestinal tract maturation of newborn. Once installed, indigenous microbiota maintains this modulation and also protects against infectious aggression. Due to these abilities, gut microbiota can be considered a 'microbial organ' that contributes to health of human host.
Francisco J, Penna   +3 more
openaire   +2 more sources

The Gastric Mucosal Barrier

Mayo Clinic Proceedings, 1975
The gastric mucosal barrier was a topic studied by many physiologists and clinicians in the 1960s and 1970s. I began my own work on it in early 1963, and when I stopped in the early 1980s I summarized my accomplishments in a book called The Gastric Mucosal Barrier: A Swan Song.
openaire   +2 more sources

The gastric mucosal barrier.

Methods and findings in experimental and clinical pharmacology, 1989
The gastric mucosal barrier is a complex system made up of submucosal, epithelial and mucus elements. The mucus gel layer is a thick tenacious organized layer adherent to the epithelium. Despite these properties it is composed of more than 95% water, the organization being provided by long interacting glycoprotein molecules (mucus glycoprotein or mucin)
J R, Clamp, D, Ene
openaire   +3 more sources

Mucosal barrier and immune mediators

Current Opinion in Gastroenterology, 2001
The intestinal mucosa functions is an immunologic organ that plays a major role in the development of oral tolerance and host-defense mechanisms. Antigens must cross the intestinal epithelium in a controlled manner to interact with dendritic antigen-presenting cells, because bacteria or their products are a primary risk factor for the development of ...
T, Sakaguchi, S, Brand, H C, Reinecker
openaire   +2 more sources

Duodenal Mucosal Barrier in Functional Dyspepsia

Clinical Gastroenterology and Hepatology, 2022
In addition to gastric sensorimotor dysfunctions, functional dyspepsia (FD) is also variably associated with duodenal micro-inflammation and epithelial barrier dysfunction, the pathogenesis and clinical significance of which are unknown. Our hypothesis was that miRNAs and/or inflammation degrade epithelial barrier proteins, resulting in increased ...
Susrutha Puthanmadhom Narayanan   +6 more
openaire   +2 more sources

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