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Interactions of commensal and pathogenic microorganisms with the intestinal mucosal barrier
The intestinal mucosal barrier is composed of epithelial cells that are protected by an overlying host-secreted mucous layer and functions as the first line of defence against pathogenic and non-pathogenic microorganisms. Some microorganisms have evolved
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Medical Journal of Australia, 1985
The 'gastric mucosal barrier' is a descriptive term for the ability of the gastric epithelium to hold a large (10(5)) H+ concentration gradient from lumen to mucosa under physiological conditions. Compounds which classically have been used to describe the functional integrity of the 'barrier', in addition to very low H+ diffusion from lumen to mucosa ...
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The 'gastric mucosal barrier' is a descriptive term for the ability of the gastric epithelium to hold a large (10(5)) H+ concentration gradient from lumen to mucosa under physiological conditions. Compounds which classically have been used to describe the functional integrity of the 'barrier', in addition to very low H+ diffusion from lumen to mucosa ...
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The pancreatic duct mucosal barrier
The American Journal of Surgery, 1979The main pancreatic duct in cats possesses a relatively strong barrier to the diffusion of bicarbonate ions (HCO3-). We studied some of the characteristics of this barrier by perfusing the duct with a solution similar in composition to pancreatic juice before and after exposing the duct mucosa to various test agents. The difference in net flux of HCO3-
H A, Reber, C, Roberts, L W, Way
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The gastric mucosal barrier and ulceration
Brain Research Bulletin, 1980The gastric mucosal barrier is that property which defends against acid and which impedes diffusion of acid from the lumen into the mucosa. The disappearance of luminal H+ is linearly related to luminal (H+) both in the normal stomach and in stomachs exposed to barrier breakers. The latter invaribaly produce anatomic evidence of surface cellular injury.
W, Silen, R, Schiessel, E, Kivilaakso
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Probiotics and mucosal barrier in children
Current Opinion in Clinical Nutrition & Metabolic Care, 2008Colonization by the microbiota plays an important role in intestinal tract maturation of newborn. Once installed, indigenous microbiota maintains this modulation and also protects against infectious aggression. Due to these abilities, gut microbiota can be considered a 'microbial organ' that contributes to health of human host.
Francisco J, Penna +3 more
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Mayo Clinic Proceedings, 1975
The gastric mucosal barrier was a topic studied by many physiologists and clinicians in the 1960s and 1970s. I began my own work on it in early 1963, and when I stopped in the early 1980s I summarized my accomplishments in a book called The Gastric Mucosal Barrier: A Swan Song.
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The gastric mucosal barrier was a topic studied by many physiologists and clinicians in the 1960s and 1970s. I began my own work on it in early 1963, and when I stopped in the early 1980s I summarized my accomplishments in a book called The Gastric Mucosal Barrier: A Swan Song.
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Methods and findings in experimental and clinical pharmacology, 1989
The gastric mucosal barrier is a complex system made up of submucosal, epithelial and mucus elements. The mucus gel layer is a thick tenacious organized layer adherent to the epithelium. Despite these properties it is composed of more than 95% water, the organization being provided by long interacting glycoprotein molecules (mucus glycoprotein or mucin)
J R, Clamp, D, Ene
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The gastric mucosal barrier is a complex system made up of submucosal, epithelial and mucus elements. The mucus gel layer is a thick tenacious organized layer adherent to the epithelium. Despite these properties it is composed of more than 95% water, the organization being provided by long interacting glycoprotein molecules (mucus glycoprotein or mucin)
J R, Clamp, D, Ene
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Mucosal barrier and immune mediators
Current Opinion in Gastroenterology, 2001The intestinal mucosa functions is an immunologic organ that plays a major role in the development of oral tolerance and host-defense mechanisms. Antigens must cross the intestinal epithelium in a controlled manner to interact with dendritic antigen-presenting cells, because bacteria or their products are a primary risk factor for the development of ...
T, Sakaguchi, S, Brand, H C, Reinecker
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Duodenal Mucosal Barrier in Functional Dyspepsia
Clinical Gastroenterology and Hepatology, 2022In addition to gastric sensorimotor dysfunctions, functional dyspepsia (FD) is also variably associated with duodenal micro-inflammation and epithelial barrier dysfunction, the pathogenesis and clinical significance of which are unknown. Our hypothesis was that miRNAs and/or inflammation degrade epithelial barrier proteins, resulting in increased ...
Susrutha Puthanmadhom Narayanan +6 more
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