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Development Of The Gastrointestinal Mucosal Barrier

Nutrition Reviews, 2009
In young rabbits, advancing age and natural feeding promote the development of an efficient mucosal barrier capable of protecting the host's circulation from penetration by potentially antigenic macromolecules.
openaire   +2 more sources

HIV infection and the intestinal mucosal barrier

Annals of the New York Academy of Sciences, 2012
HIV infection induces a barrier defect of the intestinal mucosa, which is closely linked to immune activation and CD4 T cell depletion. The HIV‐induced barrier defect is initiated in early acute and maintained through chronic infection. In acute infection, increased epithelial permeability is associated with increased epithelial apoptosis possibly ...
Hans-Jörg, Epple, Martin, Zeitz
openaire   +2 more sources

Characterization of the Barrier Properties of Mucosal Membranes

Journal of Pharmaceutical Sciences, 1990
The barrier properties of the nasal, rectal, and vaginal membranes were investigated in the rabbit by comparing physical characteristics and permeability to model hydrophilic and lipophilic compounds. It was found that the nasal, rectal, and vaginal mucosae differ in their physical characteristics and interactions.
D C, Corbo, J C, Liu, Y W, Chien
openaire   +2 more sources

Intestinal Inflammation and Mucosal Barrier Function

Inflammatory Bowel Diseases, 2014
Intestinal mucosal barrier function is the capacity of the intestine to provide adequate containment of luminal microorganisms and molecules while preserving the ability to absorb nutrients. The central element is the epithelial layer, which physically separates the lumen and the internal milieu and is in charge of vectorial transport of ions ...
Fermín, Sánchez de Medina   +3 more
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Salicylate Damage to the Gastric Mucosal Barrier

New England Journal of Medicine, 1967
EVER since Reaumur, more than two centuries ago, discovered that gastric juice digests meat, men have asked: "Why doesn't the stomach digest itself?" There are two answers to this question. One is, of course, that sometimes the stomach does digest itself, with disastrous consequences.
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The mucosal immune system at the gastrointestinal barrier

Best Practice & Research Clinical Gastroenterology, 2008
The immune system faces a considerable challenge in its efforts to maintain tissue homeostasis in the intestinal mucosa. It is constantly confronted with a large array of antigens, and has to prevent the dissemination and proliferation of potentially harmful agents while sparing the vital structures of the intestine from immune-mediated destruction ...
Schenk M, Mueller C
openaire   +3 more sources

The effect of metiamide on the gastric mucosal barrier

Journal of Surgical Research, 1977
Abstract The effect of Metiamide, an H2-receptor antagonist, on the hydrogen ion back diffusion and transmucosal electrical potential difference was tested in the nonsecreting in vitro frog gastric mucosa. Under the conditions of this study, the topical application of Metiamide did not effect either hydrogen ion back diffusion or transmucosal ...
R, Drew, T, Freeman, R P, Fischer
openaire   +2 more sources

A physical identity for the gastric mucosal barrier

Medical Journal of Australia, 1990
An oligolamellar lining which is probably phospholipid has been demonstrated on the gastric mucosal surface of the rat by transmission electron microscopy using fixation procedures specially developed to avoid the destruction of hydrophobic surfaces. This structure is unlikely to be an artefact since the use of two hydrophobic probes in epifluorescence
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The gastric mucosal barrier.

The Mount Sinai journal of medicine, New York, 2000
Most gastroduodenal ulcer disease results from a weakness in the normal gastric mucous barrier against the penetration of acid secreted by the stomach. Based on meticulous and insightful research, the distinguished physiologist Franklin Hollander hypothesized that the stomach is protected against its own acid secretion by a dynamic two-component mucus ...
openaire   +1 more source

Role of Goblet Cells in Intestinal Barrier and Mucosal Immunity

Journal of Inflammation Research, 2021
Songwei Yang, Min Yu
exaly  

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