Results 111 to 120 of about 56,513 (348)
Attitudes Toward Prenatal Interventions in the Fanconi Anemia Community
ABSTRACT Objective In‐utero cell and gene therapies may offer prenatal treatment options for inherited diseases. Preclinical data suggests in‐utero (IU) hematopoietic stem cell transplantation (HSCT) could prevent Fanconi anemia (FA) related bone marrow failure without genotoxic conditioning or immune suppression.
Tony Lum +4 more
wiley +1 more source
MASCC/ISOO clinical practice guidelines for the management of mucositis secondary to cancer therapy [PDF]
Data source: Supporting information, http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4164022/BACKGROUND: Mucositis is a highly significant, and sometimes dose-limiting, toxicity of cancer therapy.
Bowen, J. +13 more
core +1 more source
ABSTRACT Objective To describe the prenatal diagnosis, evolution, and perinatal management of kaposiform hemangioendothelioma (KHE) complicated by the Kasabach–Merritt phenomenon (KMP), and to report the first documented use of maternal sirolimus therapy (MST) in this setting. Methods We retrospectively reviewed four fetuses with a prenatal soft‐tissue
Antoine Fraissenon +11 more
wiley +1 more source
hESC-derived mesenchymal stem cells Promote Oral Mucositis Healing via the PI3K/AKT Pathway [PDF]
Kejia Lv +5 more
openalex +1 more source
Sickle Cell Disease: Historical Overview and Current Therapies
ABSTRACT Sickle cell disease (SCD) affects millions worldwide, yet the limited treatment options currently available do not always adequately control the disease and carry significant side effects. At present, the only curative treatment is hematopoietic stem cell (HSC) transplantation, a procedure that carries considerable challenges and numerous ...
Oluwaseun O. Babatunde +4 more
wiley +1 more source
Strategies in Management of Oral Mucositis
Oral mucositis is a clinically important and sometimes dose-limiting complication of Cancer Therapy. Mucositis lesions are painful, affect nutrition, quality of life and often hampers continuity of the treatment modality.
Sonal Vahanwala, Sandeep Pagare
core +1 more source
Mucosal Immunity/Mucosal Vaccine
ヒトや動物には,外敵から身体を守るために免疫系が備わっている.多くのウイルスや病原菌の侵入口である粘膜面には効果的な「粘膜免疫」が存在し,抗原特異的分泌型IgA応答や細胞障害性T細胞(CTL)を誘導する.各粘膜は共通粘膜免疫機構(common mucosal immune system(CMIS))により関連をもち,ある粘膜組織で誘導されたIgA産生細胞やCTLは他の粘膜組織にも帰巣(ホーミング)する.とくに,分泌型IgA産生細胞は,腸管関連リンパ組織(GALT),鼻咽頭関連リンパ組織(NALT)および気管支関連リンパ組織(BALT)などの誘導組織(inductive site)で誘導され,実効組織(effector site)である腸管粘膜固有層,呼吸器粘膜固有層,乳腺,涙腺,唾液腺 ...
openaire +2 more sources
Effects of an Oral Mucosa Protective Formulation on Chemotherapy- and/or Radiotherapy-induced Oral Mucositis: A Prospective Study [PDF]
Takao Ueno +4 more
openalex +1 more source
Kaposiform hemangioendothelioma: Diagnosis and treatment
Vascular endothelial growth factor‐C (VEGF‐C)/vascular endothelial growth factor receptor‐3 (VEGFR‐3) and angiopoietin‐2 (Ang‐2)/tyrosine kinase with immunoglobulin‐like and EGF‐like domain 2 (TIE2) signaling pathways play an important role in lymphangiogenesis.
Yi Tian +5 more
wiley +1 more source

