Results 131 to 140 of about 48,706 (299)

Red lines and green lights: Gene therapy for inherited erythroid disorders beyond the haemoglobinopathies

open access: yesBritish Journal of Haematology, EarlyView.
Gene therapy is revolutionizing treatment paradigms for haemoglobinopathies, establishing a translational framework for disorders that impact red blood cell development. In their paper, Joshi et al. describe the preclinical and early clinical landscape of gene therapies for non‐haemoglobinopathy erythroid disorders and highlight common thematic ...
Gaurav Joshi   +3 more
wiley   +1 more source

Cancer pain: current practice and emerging targets

open access: yesBritish Journal of Pharmacology, EarlyView.
Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye   +5 more
wiley   +1 more source

Cancer treatment-induced oral mucositis [PDF]

open access: yes, 2007
Oral mucositis is one of the main complications in non-surgical cancer treatments. It represents the major dose-limiting toxicity for some chemotherapeutic agents, for radiotherapy of the head and neck region and for some radiochemotherapy combined ...
D. Alterio   +5 more
core  

Gasdermin‐Mediated Pyroptosis: Novel Strategies Against Colorectal Cancer

open access: yesCancer Science, EarlyView.
Pyroptosis is a double‐edged sword in colorectal cancer (CRC): chronic low‐grade pyroptosis promotes tumor progression, whereas acute induction of pyroptosis in cancer cells triggers antitumor immunity and enhances therapeutic response. Targeting gasdermin‐mediated pyroptosis represents a promising strategy for CRC treatment.
Kaibo Guo   +6 more
wiley   +1 more source

L‐VISP: LSTM Visualization for Interpretable Symptom Prediction in Patient Cohorts

open access: yesComputer Graphics Forum, EarlyView.
L‐VISP is a human‐machine solution that uses visual analytics for LSTM modelling in clinical research. L‐VISP uses custom visual encodings to make multiple LSTM variants interpretable, supporting a full range of analysis, from understanding model operations and evaluating performance to interpreting results in a clinical context.
C. Floricel   +6 more
wiley   +1 more source

ٍEvaluating Baremoom Mouthwash Efficacy in Treatment of Chemotherapy-Induced Mucositis

open access: yesMajallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, 2016
Introduction: Chemotherapy-induced oral mucositis is regarded as a painful and discomforting chemotherapy complication , affecting patient’s quality of life and endurance to continue the treatment.
MH Akhavan Karbasi   +3 more
doaj  

Mucosal syphilide

open access: yesIndian Journal of Dermatology, Venereology and Leprology, 2023
Neirita, Hazarika   +2 more
openaire   +2 more sources

Ten‐Year Post‐Loading Outcomes of Subcrestally Placed Implants With Internal Conical Connections at 0.5 mm Versus 1.5 mm Depth: A Multicentre Within‐Person Randomised Controlled Trial

open access: yesClinical Oral Implants Research, EarlyView.
ABSTRACT Objectives To evaluate whether placing single dental implants either 0.5 or 1.5 mm subcrestally in healed bone crests confers any clinical benefits. Materials and Methods Sixty partially edentulous patients requiring two single implant‐supported crowns were enrolled in a split‐mouth design across six centres. Each site was randomly assigned to
Marco Esposito   +9 more
wiley   +1 more source

Effect of Oral Cryotherapy on Combination Chemotherapy-induced Oral Mucositis: A Randomized Clinical Trial

open access: yesMiddle East Journal of Cancer, 2012
Background: This study assesses the effect of oral cryotherapy on the incidence and severity of chemotherapy-induced oral mucositis in combined chemotherapy regimens.Methods: This was a randomized controlled trial that enrolled 80 cancer patients.
Abbas Heydari   +2 more
doaj  

A Randomised Controlled Trial Comparing a One‐Piece Zirconia Tissue‐Level Implant and Two‐Piece Titanium Bone‐Level Implant for Maxillary Single Tooth Replacement—3 year Results

open access: yesClinical Oral Implants Research, EarlyView.
ABSTRACT Objectives This RCT evaluated and compared the clinical performance of zirconia and titanium dental implants placed in the maxillary premolar region. Outcomes were assessed 3 years after prosthetic loading and included marginal bone level (MBL) changes, clinical parameters, aesthetic outcomes, and patient related outcome measures (PROMs ...
J. H. W. de Beus   +8 more
wiley   +1 more source

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