Results 51 to 60 of about 5,720 (215)

The Diagnosis and Blistering Mechanisms of Mucous Membrane Pemphigoid

Frontiers in Immunology, 2019
Mucous membrane pemphigoid (MMP) is a mucous membrane-dominated autoimmune subepithelial blistering disease that is caused by autoantibodies against various autoantigens in basement membrane zone (BMZ) proteins, including collagen XVII (COL17 ...
Mayumi Kamaguchi, Mayumi Kamaguchi, Hiroaki Iwata   +2 more
doaj   +1 more source

Providing Adapted Care for Patients with Immune-mediated Mucous Membrane Conditions. [PDF]

, 2015
PosterBackground: Immune-mediated diseases frequently manifest in the oral mucosa, which may be the first clinical sign for many patients. Some of these diseases present in ways that are pathognomonic (specific) for the condition; however, others have ...
Bailey, Scheri, Bailey, Scheri, Taylor, Heather   +2 more
core  

Protease inhibitors prevent plasminogen-mediated, but not pemphigus vulgaris-induced, acantholysis in human epidermis [PDF]

, 2003
Pemphigus is an autoimmune blistering disease of the skin and mucous membranes. It is caused by autoantibodies directed against desmosomes, which are the principal adhesion structures between epidermal keratinocytes.
Besch, R., Braungart, E., Degitz, K., Douwes, K., Flaig, M. J., Magdolen, V., Probst, C., Sander, C. A., Schuh, T., Wosikowski, K.   +9 more
core   +1 more source

European S2k guidelines on management of autoimmune blistering diseases in children and adolescents

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Autoimmune blistering disorders (AIBDs) in children are rare, challenging to diagnose and treat and often require immunosuppressants. Until now, no paediatric care guidelines existed. The EADV Task Force for AIBDs has developed the consensus‐based recommendations, enabling physicians to adopt a uniform, tailored treatment strategy to improve outcomes ...
A. Nanda, B. Tedbirt, C. Bodemer, M. C. Bolling, M. El Hachem, M. Nikolić, E. Benton, M. Caproni, D. De, D. Didona, K. Drenovska, M. Goebeler, M. Hertl, B. Horváth, M. Kasperkiewicz, D. Kiritsi, M. Larralde, A. V. Marzano, J. Meijer, D. F. Murrell, J. Powell, E. Sprecher, N. S. Chandran, M. M. Tomayko, S. Uzun, N. van Beek, H. Ott, A. Patsatsi, A. Torrelo, A. Welfringer‐Morin, E. Schmidt, P. Joly   +31 more
wiley   +1 more source

IgE autoantibodies and their association with the disease activity and phenotype in Bullous Pemphigoid: a systematic review [PDF]

, 2017
Bullous Pemphigoid (BP) is the most common autoimmune skin disease of blistering character. The underlying pathophysiological mechanism involves an immune attack, usually by IgG class autoantibodies, on the autoantigen BP 180/BPAg2, which is a type XVII ...
Fairclough, Lucy C., Hadjikyriacou Saniklidou, Ariadne, Tighe, Patrick J., Todd, Ian   +3 more
core   +2 more sources

Incidence of P200 pemphigoid: A nationwide study

Journal of the European Academy of Dermatology and Venereology, EarlyView.
The anti‐LAMB4 cell‐based immunoassay is a new serological technique that is far superior to dermal immunoblotting for detecting autoantibodies directed against the P200 protein. This method allows a re‐evaluation of the incidence of P200 pemphigoid, which appears to be considerably more frequent than epidermolysis bullosa acquisita.
Fabienne Jouen, Marion Carrette, Marie‐Laure Golinski, Maud Maho‐Vaillant, Alexis Lefebvre, André Gillibert, Pascal Joly, Vivien Hébert   +7 more
wiley   +1 more source

Two pemphigoid cases with mucous membrane involvement successfully treated with baricitinib

JEADV Clinical Practice
Both bullous pemphigoid and mucous membrane pemphigoid are autoimmune bullous diseases that can be challenging to treat in individual cases. Janus kinase inhibitors have shown efficacy in several autoimmune and inflammatory diseases, although these drugs
Tamás Malkovics, Orsolya N. Horváth, Miklós Sárdy   +2 more
doaj   +1 more source

Coexistence of mucous membrane pemphigoid and vitiligo

Indian Dermatology Online Journal, 2014
Mucous membrane pemphigoid describes a rare heterogeneous group of chronic, inflammatory, mucous membrane-dominated, subepithelial blistering diseases that manifest a varying constellation of oral, ocular, skin, genital, nasopharyngeal, esophageal, and ...
Sanath Aithal, Satyaki Ganguly, Sheela Kuruvila   +2 more
doaj   +1 more source

Oral Pemphigoid Recalcitrant Lesion Treated with PRGF Infiltration. Case Report

Dentistry Journal, 2021
Mucous membrane pemphigoid (MMP) is a heterogeneous group of chronic autoimmune subepithelial blistering diseases. Oral involvement is present in almost all patients, may represent the onset of the disease, and causes different degrees of pain, dysphagia,
Eduardo Anitua, Mohammad H. Alkhraisat, Asier Eguia, Laura Piñas   +3 more
doaj   +1 more source

Diagnostic Agreement in Subepidermal Blistering Diseases: Is ELISA Test Reliable as Direct Immunofluorescence? A Systematic Review, Meta‐Analysis, and Trial Sequential Analysis

Journal of Oral Pathology &Medicine, EarlyView.
ABSTRACT Objectives Direct immunofluorescence (DIF) is the gold standard for diagnosing subepidermal blistering diseases (SBDs). However, DIF requires specialized expertise; therefore, alternative immunological methods such as enzyme‐linked immunosorbent assays (ELISA) are worth exploring. The aim of this review was to evaluate the diagnostic agreement
Romeo Patini, Gioele Gioco, Michele Davide Mignogna, Stefania Leuci, Francesco Scilla, Davide Gentile, Cosimo Rupe, Enrico Russo, Anna Schiavelli, Carlo Lajolo   +9 more
wiley   +1 more source