Results 61 to 70 of about 2,097 (184)

Protection‐Free, Two‐step Synthesis of C5‐C Functionalized Pyrimidine Nucleosides

Current Protocols, Volume 4, Issue 2, February 2024.
Abstract A simple, reliable, and efficient method for the gram‐scale chemical synthesis of pyrimidine nucleosides functionalized with C5‐carboxyl, nitrile, ester, amide, or amidine, starting from unprotected uridine and cytidine, is described. The protocol involves the synthesis of 5‐trifluoromethyluridine and 5‐trifluoromethylcytidine with Langlois ...
Karolina Podskoczyj, Anna Kuszczynska, Agnieszka Dziergowska, Grazyna Leszczynska   +3 more
wiley   +1 more source

Stigma and cystic fibrosis Estigma y fibrosis cística Estigma e fibrose c��stica

Revista Latino-Americana de Enfermagem, 2010
Cystic Fibrosis (CF), also known as Mucoviscidosis, is a chronic disease of autosomal recessive origin and so far incurable. This analysis considers some characteristics of patients and family members that indicate it is a stigmatizing disease.
Tainá Maues Peluci Pizzignacco, Débora Falleiros de Mello, Regina Aparecida Garcia de Lima   +2 more
doaj   +1 more source

Predictive Factors of Abdominal Compartment Syndrome in Neonatal Age [PDF]

, 2014
In the pediatric population, abdominal compartment syndrome (ACS) is a known complication of abdominal wall defect repair. However, there are only few reports on ACS in newborns and only a proposal of critical intra-abdominal pressure value (IAP) in term
Corsello, G., Giuffre, M., La Placa, S., Ortolano, R., Pinello, G., Piro, E., Schierz, I., Siracusa, F.   +7 more
core   +1 more source

Consequences of cystic fibrosis transmembrane regulator mutations on inflammatory cells [PDF]

, 2016
Recent studies in cystic fibrosis (CF) transmembrane regulator (CFTR) mutations and function have shed light on its involvement in disease progression. The extent of cell and tissue distribution of CFTR facilitates systemic dysfunction of ion transport ...
Castro, Guillermo Raul, Grumelli, Sandra, Islan, German Abel   +2 more
core   +1 more source

Polysaccharides and mucin 5AC (MUC5AC) expression in gallbladder mucosa of young patients with gallstones as evaluated by spatial visualization and quantification [PDF]

, 2010
The study aimed at examination of tissue expression of polysaccharides and secretory mucin 5AC (MUC5AC)in young patients (up to 25 years of age) with a symptomatic gallstones.
Agnieszka Adamek, Agnieszka Seraszek, Aldona Kasprzak, Celina Helak-£apaj, Elzbieta Kaczmarek, Maciej Zabel, Wojciech Malkowski   +6 more
core   +2 more sources

Safety, Tolerability, and Effects of Sodium Bicarbonate Inhalation in Cystic Fibrosis. [PDF]

, 2020
BACKGROUND:Among the many consequences of loss of CFTR protein function, a significant reduction of the secretion of bicarbonate (HCO3-) in cystic fibrosis (CF) is a major pathogenic feature.
Clinckspoor, Karl Jan, Conrad, Douglas, Gomez, Carla Cristina Souza, Levy, Carlos Emilio, Marson, Fernando Augusto Lima, Mauch, Renan Marrichi, Parazzi, Paloma Lopes Francisco, Peixoto, Andressa Oliveira, Pessine, Francisco Benedito Teixeira, Quinton, Paul Marquis, Ribeiro, Antônio Fernando, Ribeiro, José Dirceu, Ribeiro, Maria Ângela Gonçalves Oliveira   +12 more
core   +1 more source

Microbes Saving Lives and Reducing Suffering

Microbial Biotechnology, Volume 18, Issue 1, January 2025.
Kenneth Timmis, Zeynep Ceren Karahan, Juan Luis Ramos, Omry Koren, Ana Elena Pérez‐Cobas, Karen Steward, Victor de Lorenzo, Elisabetta Caselli, Margaret Douglas, Clarissa Schwab, Virginia Rivero, Rafael Giraldo, Junkal Garmendia, Raymond J. Turner, Jessamyn Perlmutter, José M. Borrero de Acuña, Pablo Ivan Nikel, Jerome Bonnet, Angela Sessitsch, James K. Timmis, Carla Pruzzo, M. Auxiliadora Prieto, Siavash Isazadeh, Wei E. Huang, Gerard Clarke, Danilo Ercolini, Max Häggblom   +26 more
wiley   +1 more source

Sleep habits and pattern in 1-14 years old children and relationship with video devices use and evening and night child activities [PDF]

, 2017
Background: Sleep in childhood and adolescence is crucial for mental and physical health; however several researches reported an increasing trend towards a sleep deprivation in this age. Due to the lack of recent epidemiological studies in Italy, the aim
Bernasconi, Sergio, Bona, Gianni, Brambilla, Paolo, Bruni, Oliviero, Chiappini, Elena, Di Mauro, Giuseppe, Giussani, Marco, IUGHETTI, Lorenzo, Maffeis, Claudio, Manzoni, Paola, Miraglia Del Giudice, Emanuele, Pasinato, Angela, Picca, Marina, Privitera, Francesco, Sollai, Sara, Venturelli, Leonello   +15 more
core   +1 more source

Treatment adherence in individuals with cystic fibrosis: An Observational Study

Jornal de Assistência Farmacêutica e Farmacoeconomia
Introduction: Low treatment adherence is a complex issue frequently observed in cystic fibrosis (CF) patients. Objective: To evaluate the self-reported treatment adherence rate and the rate determined based on pharmacy medication dispensation records in
Fernanda Fontelle, LUCAS VIEIRA, ADRIANA FAIÇAL, JULIANA BRAZIL, MARCIA TEIXEIRA, EDNA LUCIA SOUZA   +5 more
doaj   +1 more source

Acceso venoso central mediante cápsulas de inyección subcutáneas. Serie de 124 dispositivos [PDF]

, 1991
Presentamos una serie de 111 pacientes (límites: 9 meses - 78 años) en los que se colocaron 124 dispositivos como modalidad de acceso venoso central. Se analizan las complicaciones aparecidas durante su utilización, que actualmente sobrepasa los 1.100 ...
Albiach, M. (M.), Balen, E. (Enrique), Benito, C. (C.), Gonzalez, J. (J.), Hernandez-Lizoain, J.L. (Jose Luis), Pardo, F. (Fernando), Voltas, J. (J.), Álvarez-Cienfuegos, J. (Javier)   +7 more
core