Results 91 to 100 of about 388,969 (398)

Epithelial miR-141 regulates IL-13–induced airway mucus production

JCI Insight, 2021
IL-13–induced goblet cell metaplasia contributes to airway remodeling and pathological mucus hypersecretion in asthma. miRNAs are potent modulators of cellular responses, but their role in mucus regulation is largely unexplored.
S. Siddiqui, K. Johansson, A. Joo, L. Bonser, Kyung Duk Koh, O. Le Tonquèze, S. Bolourchi, Rodriel A. Bautista, L. Zlock, Theodore L. Roth, A. Marson, N. Bhakta, K. Ansel, W. Finkbeiner, D. Erle, P. Woodruff   +15 more
semanticscholar   +1 more source

Bio‐Inspired Molecular Events in Poly(Ionic Liquids)

Advanced Functional Materials, EarlyView.
Originating from dipolar and polar inter‐ and intra‐chain interactions of the building blocks, the topologies and morphologies of poly(ionic liquids) (PIL) govern their nano‐ and micro‐processibility. Modulating the interactions of cation‐anion pairs with aliphatic dipolar components enables the tunability of properties, facilitated by “bottom‐up ...
Jiahui Liu, Marek W. Urban
wiley   +1 more source

Bacterial Communities in Tissues and Surficial Mucus of the Cold-Water Coral Paragorgia arborea

Frontiers in Marine Science, 2018
Coral bacterial associates can play important functional roles for the holobiont, such as nitrogen cycling, nutrient processing, and supporting immunity.
Bradley A. Weiler, Joost T. P. Verhoeven, Suzanne C. Dufour   +2 more
doaj   +1 more source

Accuracy of the Ovulon Fertility Monitor to Predict and Detect Ovulation [PDF]

, 1998
The purpose of this pilot study was to correlate the three biologic markers of the Ovulon fertility monitor (a long-term predictive peak about 6 days before ovulation, a short-term predictive peak about 1 day before ovulation, and a nadir at the time of ...
Fehring, Richard, Schlaff, William D
core   +1 more source

Membrane Fusion‐Inspired Nanomaterials: Emerging Strategies for Infectious Disease and Cancer Diagnostics

Advanced Healthcare Materials, EarlyView.
Membrane fusion‐inspired nanomaterials offer transformative potential in diagnostics by mimicking natural fusion processes to achieve highly sensitive and specific detection of disease biomarkers. This review highlights recent advancements in nanomaterial functionalization strategies, signal amplification systems, and stimuli‐responsive fusion designs,
Sojeong Lee, Khulan Nyamzaya, Jueun Han, Yejin Song, Jihee Lee, Jung Hyun Jo, Seungmin Bang, Eun‐Kyung Lim, Seungjoo Haam, Eunjung Kim   +9 more
wiley   +1 more source

The Role of Glycans in Bacterial Adhesion to Mucosal Surfaces: How Can Single-Molecule Techniques Advance Our Understanding?

Microorganisms, 2018
Bacterial adhesion is currently the subject of increased interest from the research community, leading to fast progress in our understanding of this complex phenomenon.
Cécile Formosa-Dague, Mickaël Castelain, Hélène Martin-Yken, Karen Dunker, Etienne Dague, Marit Sletmoen   +5 more
doaj   +1 more source

Mucus Plugs and Emphysema in the Pathophysiology of Airflow Obstruction and Hypoxemia in Smokers.

American Journal of Respiratory and Critical Care Medicine, 2020
BACKGROUND The relative roles of mucus plugs and emphysema in mechanisms of airflow limitation and hypoxemia in smokers with chronic obstructive pulmonary disease (COPD) are uncertain.
E. Dunican, Brett M. Elicker, T. Henry, D. Gierada, M. Schiebler, W. Anderson, I. Barjaktarevic, R. G. Barr, E. Bleecker, Richard C. Boucher, R. Bowler, S. Christenson, A. Comellas, C. Cooper, D. Couper, Gerard J. Criner, M. Dransfield, Claire M Doerschuk, M. B. Drummond, N. Hansel, M. Han, Annette T. Hastie, Eric A. Hoffman, Jerry A Krishnan, Stephen C. Lazarus, F. Martinez, Charles E. McCulloch, W. O’Neal, Victor E. Ortega, R. Paine, S. Peters, J. Schroeder, Prescott G. Woodruff, J. Fahy   +33 more
semanticscholar   +1 more source

Strategies to Improve the Lipophilicity of Hydrophilic Macromolecular Drugs

Advanced Healthcare Materials, EarlyView.
Hydrophilic macromolecular drugs can be successfully lipidized by covalent attachment of lipids, by hydrophobic ion pairing with negatively or positively charged surfactants, and by dry or wet reverse micelle formation. Lipophilicity enhancement of hydrophilic macromolecules has several benefits including stability and bioavailability improvement ...
Sera Lindner, Stefan Keim, Soheil Haddadzadegan, Odile Fernandez Romero, Katrin Zöller, Gabriel Stern, Ilaria Cesi, Krum Kafedjiiski, Andreas Bernkop‐Schnürch   +8 more
wiley   +1 more source

Enhancing Mucus Flow and Clearance by Grafting Zwitterionic Hydrogel Films to Luminal Surfaces

Laryngoscope Investigative Otolaryngology
Objective To determine the effects of zwitterionic hydrogel films on mucus contact angles, flow, and stasis with respect to medical polymer surfaces, both flat and tubular.
Ryan Horne, Caleb Escudero, Morgan Ellerman, C. Allan Guymon, Marlan Hansen   +4 more
doaj   +1 more source

Efeito do etanol e do peróxido de hidrogênio intragástrico sobre a mucosa gástrica de rã (Rana catesbeiana, SHAW) Effect of intragastric ethanol and hydrogen peroxide in frog gastric mucosa (Rana catesbeiana, SHAW)

Brazilian Archives of Biology and Technology, 1998
This work investigated the frog gastric mucosa response to hydrogen peroxide and ethanol induced injury. Acid and mucus secretion were estimated "in vitro" in control animals with intragastric absolute ethanol (1ml/30min.
Hidê Virgínia Estivallet, Maria Inês Rodrigues, Norma Possa Marroni   +2 more
doaj   +1 more source