Results 61 to 70 of about 388,969 (398)

Mucus and ciliated cells of human lung : splitting strategies for particle methods and 3D stokes flows [PDF]

, 2012
Lung walls are covered by a film of mucus, whose motility is fundamental for a healthy behavior. Indeed, mucus traps inhaled aerosols (bacteria, dust, ...), and moves from smallest to largest airways, until it reaches esophagus where is it swallowed or ...
Anne-Archard, Dominique, Chatelin, Robin, Didier, Alain, Murris-Espin, Marlène, Poncet, Philippe, Thiriet, Marc   +5 more
core  

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

MUCOLYTIC ACTIVITY OF ROSELLE (Hibiscus sabdariffa L.) CALYCES EXTRACT ON COW INTESTINAL MUCUS

Jurnal Kedokteran Hewan, 2018
This study aimed to examine the mucolytic activity of roselle calyces extract on cow intestinal mucus in vitro. The extraction of roselle calyces was performed by the subsequence maceration method using different polarity solvent (n-hexane, ethyl acetate,
Nerdy Nerdy, Kesaktian Manurung
doaj   +1 more source

Across the mucus

Nature Reviews Microbiology, 2022
This study reports that SARS-CoV-2 binds to cilia and reprogrammes microvilli to promote replication in the nasal airway.
openaire   +2 more sources

Lipid Nanoparticles for the Delivery of CRISPR/Cas9 Machinery to Enable Site‐Specific Integration of CFTR and Mutation‐Agnostic Disease Rescue

Advanced Functional Materials, EarlyView.
Lipid nanoparticles (LNPs) are optimized to co‐deliver Cas9‐encoding messenger RNA (mRNA), a single guide RNA (sgRNA) targeting the endogenous cystic fibrosis transmembrane conductance regulator (CFTR) gene, and homologous linear double‐stranded donor DNA (ldsDNA) templates encoding CFTR.
Ruth A. Foley, Paul G. Ayoub, Vrishti Sinha, Colin Juett, Alicia Sanoyca, Emily C. Duggan, Lindsay E. Lathrop, Priyanka Bhatt, Kevin Coote, Beate Illek, Brigitte N. Gomperts, Donald B. Kohn, Steven J. Jonas   +12 more
wiley   +1 more source

Planarian Mucus: A Novel Source of Pleiotropic Cytotoxic and Cytostatic Agents against Cancer Cells

Biomolecules
Biological evolution has generated a vast array of natural compounds produced by organisms across all domains. Among these, secondary metabolites, selected to enhance an organism’s competitiveness in its natural environment, make them a reservoir for ...
Gaetana Gambino, Eleonora Da Pozzo, Alessandra Salvetti, Leonardo Rossi   +3 more
doaj   +1 more source

Recent Insights into the Management of Inflammation in Asthma [Letter]

Journal of Inflammation Research, 2021
Aleksandr Urakov,1,2,* Natalya Urakova1,* 1Department of General and Clinical Pharmacology, Izhevsk State Medical Academy, Izhevsk City, Udmurt Republic, Russian Federation; 2Institute of Applied Mechanics, Udmurt Federal Research Center of the Ural ...
Urakov A, Urakova N
doaj  

Trefoil Factor Family (TFF): Peptides with Numerous Functions

Southeastern European Medical Journal, 2019
The trefoil factor family (TFF) consists of a group of small peptides and is highly expressed in tissue that contain mucus-producing cells, predominantly in the mucosa that lines the gastrointestinal tract.
Nataša Kozina, Ivana Jukić
doaj   +1 more source

Comparing the immune response to a novel intranasal nanoparticle PLGA vaccine and a commercial BPI3V vaccine in dairy calves [PDF]

, 2015
peer-reviewedBackground There is a need to improve vaccination against respiratory pathogens in calves by stimulation of local immunity at the site of pathogen entry at an early stage in life. Ideally such a vaccine preparation would not be inhibited by
A Menanteau-Horta, A Vila, AR Peters, B Morein, B Morein, Bernadette Earley, BJF Bradshaw, BM Adair, Bryan Markey, C Pilette, CA Siegrist, CX Song, DG Bryson, DP Greenberg, EM Liebler-Tenorio, F Alexis, F Mansoor, Fawad Mansoor, FM Buonaguro, HM Chen, I Vangeel, J Phillips, J Pollock, JE Crowe, Joseph P. Cassidy, JS Salt, K Tahara, KJ Wiechelman, M Garinot, M Higaki, Michael D. Welsh, ML Hans, MS Lee, OV Kavanagh, PE Shewen, PK Smith, PR Wood, RE Brown, RM Zinkernagel, S Lofthouse, Simon Doherty, TG Kimman, YJ Kwon   +42 more
core   +1 more source

The Role of the Gastrointestinal Mucus System in Intestinal Homeostasis: Implications for Neurological Disorders

Frontiers in Cellular and Infection Microbiology, 2020
Mucus is integral to gut health and its properties may be affected in neurological disease. Mucus comprises a hydrated network of polymers including glycosylated mucin proteins.
M. Herath, S. Hosie, J. Bornstein, A. Franks, E. Hill-Yardin   +4 more
semanticscholar   +1 more source