Results 101 to 110 of about 53,249 (182)

Therapeutic potential of a Bax inhibitor‐1/TMBIM6 antagonist (BIA) and its analogues in Aspergillus fumigatus‐induced asthma via dual targeting of AKT and epithelial‐derived inflammatory cytokines

British Journal of Pharmacology, Volume 183, Issue 19, Page 5975-5991, October 2026.
Background and Purpose Aspergillus fumigatus (A. fumigatus) exposure causes of severe allergic asthma, characterized by airway inflammation and epithelial dysfunction. TMBIM6 (Bax inhibitor‐1) has been implicated in airway epithelial stress responses and AKT signalling.
Young‐Jin Yu, Ahsan Ullah, Jisun Kim, Mehedi Hasan Bappi, Yerim Heo, Jin Hee Ahn, Hyun‐Kyoung Kim, Han‐Jung Chae   +7 more
wiley   +1 more source

Allergic bronchopulmonary aspergillosis manifested secondary to bacterial pleural empyema

Respirology Case Reports
A 54‐year‐old woman with no history of lung disease including bronchial asthma developed left bacterial pleural empyema due to the perforation of a lung abscess in the left lower lobe. Chest tube drainage and antibiotics improved the pleural empyema. Two
Hiromu Kawano, Keiko Kan‐o, Ayaka Egashira, Isamu Okamoto   +3 more
doaj   +1 more source

Case Report: Aspergillus fumigatus-associated plastic bronchitis in a pediatric patient with cystic fibrosis complicated by allergic bronchopulmonary aspergillosis

Frontiers in Pediatrics
While plastic bronchitis (PB) is most commonly associated with viral pathogens and Mycoplasma pneumoniae (MP) infections, fungal etiologies are exceptionally uncommon in children.
Fen Liu, Linlin Zhao, Yanpeng Gao, Xiaoyan Wang, Han Zhang   +4 more
doaj   +1 more source

Derivation and Validation of a Predictive Model for Advanced Colorectal Neoplasia Among Average‐Risk Adults in China

International Journal of Cancer, Volume 159, Issue 6, Page 1455-1463, 15 September 2026.
Efficient pre‐colonoscopy risk stratification tools are needed, especially in China. Using multicenter colorectal cancer screening data from Shandong Province, the authors developed and validated a risk prediction model for advanced colorectal neoplasia in asymptomatic individuals using sociodemographic characteristics, lifestyle factors, and medical ...
Yan Liu, Yanxiu Liu, Yukun Feng, Boyu Liu, Wenxuan Yan, Nan Zhang, Youhua Lu   +6 more
wiley   +1 more source

Rapid Fabrication of Self‐Propelled and Steerable Magnetic Microcatheters for Precision Medicine

Advanced Materials, Volume 38, Issue 51, 11 September 2026.
A rapid Joule heating fabrication method for the production of self‐propelling, adaptive microcatheters, with tunable stiffness and integrated microfluidic channels is presented. Demonstrated through three microrobotic designs, including a steerable guiding catheter, an untethered wave‐crawling TubeBot, and a distal‐end propelled microcatheter, it was ...
Zhi Chen, Boris Rivkin, David Castellanos‐Robles, Ivan Soldatov, Lukas Beyer, Mariana Medina‐Sánchez   +5 more
wiley   +1 more source

A non-invasive simplified scoring system to predict airway mucus plugs in asthma

Background Airway mucus plugs are a core pathological feature of severe asthma and are closely associated with airflow limitation and poor prognosis.
Zhen Wang, Gongqi Chen, Guohua Zhen, Wei Gu, Lixia Xia, Ruchong Chen, Huiru Jie, Chunli Huang, Yuchen Feng, Tiantian Xiong   +9 more
core   +1 more source

Functional morphology of the pharyngeal teeth of the ocean sunfish, Mola mola

The Anatomical Record, Volume 309, Issue 9, Page 2286-2297, September 2026.
Abstract Many fish use a set of pharyngeal jaws in their throat to aid in prey capture and processing, particularly of large or complex prey. In this study—combining dissection, CT scanning, histology, and performance testing—we demonstrate a novel use of pharyngeal teeth in the ocean sunfish (Mola mola), a species for which pharyngeal jaw anatomy had ...
Benjamin Flaum, Michael J. Blumer, Mason N. Dean, Laura J. Ekstrom   +3 more
wiley   +1 more source

Mucus Plug Removed Using Bronchoscopy with a Cryoprobe

Internal Medicine, 2022
Takigawa, Yuki, Watanabe, Hiromi, Kagawa, Daiki, Sato, Ken   +3 more
openaire   +2 more sources

Pregnancy‐related effect on elexacaftor, tezacaftor and ivacaftor pharmacokinetics in women with cystic fibrosis

British Journal of Clinical Pharmacology, Volume 92, Issue 9, Page 3202-3213, September 2026.
Aim The number of pregnancies among women with cystic fibrosis (wwCF) has steadily increased over the past decade. However, the pharmacokinetics (PK) of elexacaftor–tezacaftor–ivacaftor (ETI) during gestation remains uncharacterized, despite its widespread use in this population.
Paulette Magnas, Naim Bouazza, Frantz Foissac, Saïk Urien, Léo Froelicher‐Bournaud, Gabrielle Lui, Victoria Guillemart, Nicolas Carlier, Jennifer Da Silva, Johanna Fesenbeckh, Reem Kanaan, Isabelle Honoré, Clémence Martin, Jean‐Marc Treluyer, Vassilis Tsatsaris, Pierre‐Régis Burgel, Sihem Benaboud   +16 more
wiley   +1 more source

Peroxidase-mediated mucin cross-linking drives pathologic mucus gel formation in IL-13–stimulated airway epithelial cells

JCI Insight
Mucus plugs occlude airways to obstruct airflow in asthma. Studies in patients and in mouse models show that mucus plugs occur in the context of type 2 inflammation, and studies in human airway epithelial cells (HAECs) show that IL-13–activated cells ...
Maude A. Liegeois, Margaret Braunreuther, Annabelle R. Charbit, Wilfred W. Raymond, Monica Tang, Prescott G. Woodruff, Stephanie A. Christenson, Mario Castro, Serpil C. Erzurum, Elliot Israel, Nizar N. Jarjour, Bruce D. Levy, Wendy C. Moore, Sally E. Wenzel, Gerald G. Fuller, John V. Fahy   +15 more
doaj   +1 more source