Results 171 to 180 of about 104,669 (254)

Variation on Toxic and Inflammatory Potential of Coal Smoke of Different Sources From a Region With High Lung Cancer Risk

Environmental Toxicology, EarlyView.
ABSTRACT Excess lung cancer risk in Xuanwei and Fuyuan, China, has been attributed to household air pollution from use of a locally sourced smoky (bituminous) coal. However, the carcinogenic mechanisms remain unclear. Given the important role of inflammation in lung cancer development, this study compared the proinflammatory potentials of the ...
Yongliang Zhang, Wei Hu, Nathanial Rothman, Dingyu Liu, Jihua Li, Jun Xu, Bofu Ning, Roel Vermeulen, Qing Lan, Flemming R. Cassee, George S. Downward   +10 more
wiley   +1 more source

Sargassum Lung Syndrome: Air Flow Obstruction and Bronchial Inflammation Are Observed After Prolonged Exposure to Sargassum Gas Emissions in the Eastern Caribbean

Environmental Toxicology, EarlyView.
ABSTRACT Sargassum inundation of Caribbean and American shorelines is a growing environmental hazard. Hydrogen sulfide (H2S) and ammonia (NH3) produced by decomposing Sargassum could be involved in airway obstruction and bronchial inflammation. The study was undertaken to evaluate the effects of exposure to H2S and NH3 gases emitted during Sargassum ...
Rishika Banydeen, Jonathan Florentin, Maxime Boutourlinsky, Remi Nguyen, Fatima Radouani, Moustapha Agossou, Gary Lutin, Thierry Lebrun, Remi Neviere, Dabor Resiere   +9 more
wiley   +1 more source

Acid exposure disrupts mucus secretion and impairs mucociliary transport in neonatal piglet airways.

Am J Physiol Lung Cell Mol Physiol, 2020
Liao YSJ, Kuan SP, Guevara MV, Collins EN, Atanasova KR, Dadural JS, Vogt K, Schurmann V, Bravo L, Eken E, Sponchiado M, Reznikov LR.   +11 more
europepmc   +1 more source

Maternal Lead Exposure Induces Glandular Alterations in the Salivary Glands of Rat Male Offspring

Environmental Toxicology, EarlyView.
ABSTRACT Lead (Pb) is a widely distributed environmental pollutant that is highly noxious due to its toxicokinetic characteristics. Pb exposure can damage vital organ systems, including the central nervous and stomatognathic systems. As salivary glands play an important role in oral homeostasis, this study aimed to investigate the effects of maternal ...
Rayssa Maitê Farias Nazário, Deiweson Souza‐Monteiro, Walessa Alana Bragança Aragão, Luciana Eiró‐Quirino, Leonardo Oliveira Bittencourt, Raquel Fernanda Gerlach, Antônio Hernandes Chaves‐Neto, Michael Aschner, Rafael Rodrigues Lima   +8 more
wiley   +1 more source

From Consumer Plastics to Aquatic Toxicants: Oxidative and Endocrine Effects of Microplastics on Fathead Minnow (Pimephales promelas) Larvae

Environmental Toxicology, EarlyView.
ABSTRACT Secondary microplastics (MPs) from single‐use consumer products are rapidly becoming one of the most persistent and widespread pollutants of our time. Freshwater systems act as early sinks for MPs where fragmentation and additive leaching expose aquatic life to a broad spectrum of toxic compounds.
Alisha M. Janiga‐MacNelly, Andrew Barrick, Tham C. Hoang, Ramon Lavado   +3 more
wiley   +1 more source

Rhubarb-Evoke Mucus Secretion through Aggregation and Degranulation of Mast Cell in the Colon of Rat: In vivo and ex vivo studies. [PDF]

Sci Rep, 2019
Wu D, Xue X, Gao C, Liu Y, Wang T, Li L, Tong X, Li F, Xu J.   +8 more
europepmc   +1 more source

Cellular Mechanism and Key Insights in Allergen Immunotherapy for Allergic Rhinitis

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Allergic rhinitis (AR) arises from immune responses mediated by immunoglobulin E (IgE) to inhaled allergens, representing one of the most prevalent chronic conditions worldwide. Although AR may not be a serious ailment, it holds clinical relevance as it underpins numerous complications, serves as a major risk factor for suboptimal asthma ...
Zhe Wang, Teng‐Fei Li, Tian‐Yu Wang, Huan‐Hai Liu   +3 more
wiley   +1 more source

Stress-Induced Mucus Secretion and Its Composition by a Combination of Proteomics and Metabolomics of the Jellyfish Aurelia coerulea. [PDF]

Mar Drugs, 2018
Liu W, Mo F, Jiang G, Liang H, Ma C, Li T, Zhang L, Xiong L, Mariottini GL, Zhang J, Xiao L.   +10 more
europepmc   +1 more source

Identification and Validation of Biomarkers in Chronic Rhinosinusitis With Nasal Polyps and Study of Their Associated Mechanisms

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Cell senescence (CS) and lipid metabolism (LM) disorders have been reported in chronic rhinosinusitis with nasal polyps (CRSwNP). However, the mechanism is still unclear. Methods Data were obtained from public databases; differential expression analysis and machine learning were performed to identify biomarkers and to understand the
Hui‐Yi Deng, Hui‐Jun Qiu, Ming‐Rui Pan, Qin‐Tai Yang   +3 more
wiley   +1 more source