Results 191 to 200 of about 109,419 (254)

Diet–Microbiome–Immune Interactions at the Gut Mucosa in Food Allergy: Mechanisms, Gaps, and Therapeutic Implications

Allergy, EarlyView.
ABSTRACT Mucosal surfaces are sites of highly dynamic interactions among epithelial and immune cells, environmental exposures, particularly dietary inputs, and the diverse microbial communities and their metabolites. These elements continually influence each other to maintain homeostasis and ensure appropriate immune discrimination between pathogens ...
Clara Delaroque, Liam O'Mahony, Inge Kortekaas Krohn, Charlotte G. Mortz, Markus Ollert, Mahesh S. Desai   +5 more
wiley   +1 more source

Deficiency of Mitochondrial Fatty Acid Enzyme, CPT1A, Underlies Airway Epithelial Barrier Dysfunction in Severe Asthma

Allergy, EarlyView.
Mitochondrial fatty acid enzyme, CPT1A, is deficient in the airway epithelium of severe asthma patients. Restoration of CPT1A expression improved epithelial barrier integrity via increasing mitochondrial respiration and ATP production in airway epithelial cells. Restoration of deficient epithelial CPT1A may represent a new treatment approach for severe
Muyun Wang, Haiyang Hu, Kun Wang, Di Wu, Ximing Liao, Jing Gao, Tian Li, Wujian Xu, Shaoyong Gao, Qiang Li, Pankaj Kumar Bhavsar, Wei Gao, Kian Fan Chung   +12 more
wiley   +1 more source

Potassium Channels of the Airway Epithelium. [PDF]

Acta Physiol (Oxf)
Villanueva S, Vera E, Apablaza T, Catalán MA, Flores CA.   +4 more
europepmc   +1 more source

Obesity-related palmitic acid exacerbates IL-13-induced mucus phenotype in 16HBE airway epithelial cells via AMPK suppression. [PDF]

Transl Pediatr
Liu Q, Chang X, Jing W, Liu S.
europepmc   +1 more source

Natural Products Targeting Airway Inflammation and Mucus Hypersecretion: Molecular Mechanisms and Therapeutic Potential for Respiratory Health. [PDF]

Nutrients
Lee SG, Lee JH, Kang H.
europepmc   +1 more source

BEST4⁺ cells: a potential hub of intestinal ion transport and diarrhea manipulation. [PDF]

Adv Biotechnol (Singap)
Qu HZ, Wang XQ.
europepmc   +1 more source

Protein Corona‐Coated Crystal Silica From Sandstorms Amplifies Allergic Rhinitis by Regulating Epithelial Integrity in Mice and Human Nasal Epithelia

Allergy, EarlyView.
Cuishuang Dong, Xu Zhang, Haoyue Wang, Jiajing Cui, Shuai Han, Yibo Wang, Huanying Zhao, Yang Song, Yuan Zhang, Xiaobo Li   +9 more
wiley   +1 more source

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Airway Mucus Secretion

Physiology, 1990
Mucus secretion into the airways is mainly under vagal cholinergic control, and its volume and composition are modulated by sympathetic (adrenergic) and peptidergic mechanisms. Inflammatory mediators also change the secretion. The various compositions of mucus have been little explored, and the importance of its changes in disease is little understood.
JG Widdicombe, SE Webber
openaire   +1 more source