Results 51 to 60 of about 4,369 (198)

Familial Associations of Colorectal Cancer with Other Cancers [PDF]

, 2017
Colorectal cancer (CRC) has a strong familial component which extends to discordant cancers (ie non-CRC tumors). This is best seen in cancer syndromes such as hereditary non-polyposis colorectal cancer (HNPCC) which predisposes to several tumor types ...
Hemminki, Akseli, Hemminki, Kari, Sundquist, Kristina, Yu, Hongyao   +3 more
core   +1 more source

Muir-Torre Syndrome: case report and molecular characterization

São Paulo Medical Journal
CONTEXT: Muir-Torre syndrome is a rare autosomal dominant genodermatosis caused by mutations in the mismatch repair genes. It is characterized by the presence of sebaceous skin tumors and internal malignancies, affecting mainly the colon, rectum and ...
Carolina Alejandra Rios, Ricardo Villalon, Jorge Munoz, Monica Acuna, Lucia Cifuentes   +4 more
doaj   +1 more source

A Case of Hybrid Cellular Neurothekeoma and Perineurioma With a Folliculin Gene Mutation

Journal of Cutaneous Pathology, Volume 52, Issue 5, Page 374-378, May 2025.
ABSTRACT Hybrid peripheral nerve sheath tumors (PNSTs) are benign tumors that show features of more than one type of PNST. Benign cutaneous plexiform hybrid tumor of perineurioma and cellular neurothekeoma (BCPHTPCN) is a rare, recently described entity that shows various combinations of histomorphologic and immunophenotypic features of the PNSTs ...
Taylor J. Prechtel, Emma Brashear, Carina A. Dehner, Ahmed K. Alomari   +3 more
wiley   +1 more source

Deep intronic MSH2 variant confirms Muir-Torre subtype of Lynch syndrome

JID Innovations
Whole-genome sequencing can uncover clinically significant noncoding variants missed by standard germline testing, as demonstrated in this report in a patient with Muir–Torre syndrome, a subtype of Lynch syndrome.
Fiona Chan-Pak-Choon, Andrew Y. Shuen, Evan Weber, Lili Fu, Barbara Rivera, William D. Foulkes   +5 more
doaj   +1 more source

Primary Sclerosing Epithelioid Fibrosarcoma of the Lung in a Patient with Lynch Syndrome [PDF]

, 2018
Sclerosing epithelioid fibrosarcoma (SEF) is a rare neoplasm arising mostly in limbs and limb girdles, with a high rate of recurrence and a strong tendency to metastasize.
Jungraithmayr, Wolfgang, Leisibach, Priska, Soltermann, Alex, Weder, Walter   +3 more
core  

Recurrent GRHL fusions in a subset of sebaceoma: microscopic and molecular characterisation of eight cases

Histopathology, Volume 86, Issue 4, Page 571-584, March 2025.
Morphological features of RCOR1::GRHL2 adnexal tumour (case 4). Aims Sebaceous neoplasms constitute a group of adnexal tumours, including sebaceous adenoma, sebaceoma and sebaceous carcinoma. Although mismatch repair deficiency may be observed, the nature of the genetic alterations contributing to the development of most of these tumours is still ...
Mélanie Legrand, Baptiste Louveau, Nicolas Macagno, Maxence Mancini, Dmitry V Kazakov, Daniel Pissaloux, Franck Tirode, Anne Tallet, Samia Mourah, Quentin Lepiller, Arnaud de la Fouchardière, Pierre Sohier, Eric Frouin, Andreas von Deimling, Keisuke Goto, Bernard Cribier, Eduardo Calonje, Saleem Taibjee, Maxime Battistella, Thibault Kervarrec   +19 more
wiley   +1 more source

Sebaceous carcinoma : a case report [PDF]

, 2018
El carcinoma de células sebáceas es un tumor maligno infrecuente de la piel. Se lo clasifica en ocular y extraocular. Su importancia radica en su agresividad con altas tasas de recurrencia y metástasis.
Abaca, María Celeste, Cantú Parra, Laura, Fernandez Tapia, María, Innocenti, Alicia Carolina, Vidal, Jorgelina Natalí   +4 more
core  

Three Different Primary Cancers, Including Breast, Esophagus, and Renal in a Single Patient: A Case Report

Clinical Case Reports, Volume 13, Issue 2, February 2025.
ABSTRACT There are different combinations of multiple primary cancers; however, the combination of breast, esophagus, and renal cancer has been reported in a few cases. Given the rising prevalence of multiple primary cancers over the past decade, understanding the risk factors for early detection is crucial.
Amir Alinejad Khorram, Mohammad Soleimani, Ali Amani‐Beni, Tahmineh Mollasharifi, Reza Amani‐Beni, Farzad Allameh   +5 more
wiley   +1 more source

Do you Believe He Can Fly? Royce White and Reasonable Accommodations Under the Americans with Disabilities Act for NBA Players with Anxiety Disorder and Fear of Flying [PDF]

, 2014
This Article examines the legal ramifications of Royce White, a basketball player with general anxiety disorder and obsessive compulsive disorder, playing in the NBA.
McCann, Michael
core   +2 more sources

Rare Mimic of Conjunctivitis: Conjunctival Intraepithelial Sebaceous Carcinoma

Case Reports in Ophthalmological Medicine, Volume 2025, Issue 1, 2025.
Sebaceous carcinoma, an uncommon malignant neoplasm, often arises de novo from periocular sebaceous glands. Commonly manifesting as diffuse eyelid thickening, sebaceous carcinoma can mimic other inflammatory processes such as persistent chalazion or blepharitis.
Maedot A. Haymete, Kristen Delans, Paul Varghese, Nicholas Ramey, Douglas J. Grider, Alexander Bialasiewicz   +5 more
wiley   +1 more source