Results 61 to 70 of about 3,333 (172)

Muir-Torre Syndrome and founder Mismatch Repair genes mutations: A long gone historical genetic challenge

, 2016
A "cancer predisposing syndrome" later labeled as Hereditary Non-Polyposis Colorectal Cancer (HNPCC) or Lynch syndrome, was firstly described by Warthin, about one century ago. An increased predisposition to the development of multiple familial tumors is
MANFREDINI, Marco, PELLACANI, Giovanni, TOMASI, Aldo, PONTI, Giovanni   +3 more
core   +1 more source

RB1 inactivation in cutaneous carcinomas

Histopathology, Volume 88, Issue 4, Page 769-789, March 2026.
Among skin carcinomas, recurrent RB1 inactivation is observed in Merkel cell carcinoma, in a subset of squamous cell carcinoma with bowenoid morphology, in sebaceous carcinoma and in the recently described Wnt/beta‐catenin rosette‐forming carcinoma.
Tiffany Liv, Antoine Touzé, David Schrama, Serge Guyétant, Mahtab Samimi, Michael T Tetzlaff, Benjamin A Wood, Paul W Harms, Thibault Kervarrec   +8 more
wiley   +1 more source

Biallelic MYH germline mutations as cause of Muir-Torre syndrome

, 2010
Muir-Torre syndrome is a rare, inherited disease predisposing of gastrointestinal and cutaneous tumours, such as keratoacanthomas and sebaceous gland adenomas.
Pascual-Ramírez, J. Carlos, Andrada, Encarnación, Barberá, Víctor Manuel, Castillejo, Adela, Carrato, Alfredo, Castillejo, María Isabel, Molina-Garrido, María José, Soto, José Luis, Guillén-Ponce, Carmen, Guarinos, Carla   +9 more
core   +1 more source

Primary and Secondary Grzybowski’s Generalized Eruptive Keratoacanthoma: A New Perspective on Management, Clinical Features, and Prognosis

International Journal of Dermatology, Volume 65, Issue 3, Page 456-463, March 2026.
ABSTRACT Grzybowski's generalized eruptive keratoacanthoma (GEKA) is a rare variant of keratoacanthomas, characterized by hundreds to thousands of lesions, accompanied by pruritus, mucosal involvement, and comorbidities. Our aim was to analyze the clinical presentation, associated comorbidities, treatment strategies, and outcomes of GEKA.
Nicholas Florin Kormos, Carina Maria Petrenciu, Alin Stefan Vizitiu, Raluca Ghețe, Umer Nadir, Adrian Lucian Baican, Stanislav N. Tolkachjov   +6 more
wiley   +1 more source

Sebaceous carcinoma epidemiology, associated malignancies and Lynch/Muir-Torre syndrome screening in England from 2008 to 2018. Online only Supplementary Information.

, 2023
Online only Supplementary Information for original article published in JAAD. "Sebaceous carcinoma epidemiology, associated malignancies and Lynch/Muir-Torre syndrome screening in England from 2008 to 2018 ...
Cook, S
core   +2 more sources

Sebaceous carcinoma on the abdomen in an African-American male patient

Indian Dermatology Online Journal, 2015
Sebaceous carcinoma is a rare, aggressive cutaneous tumor most commonly involving the head and neck, especially the periorbital area. It has been associated with Muir–Torre syndrome, human papillomavirus infection, and radiotherapy.
Talitha C Moon, Nicole M Cassler, Jeffrey N Lackey   +2 more
doaj   +1 more source

A Case of Hybrid Cellular Neurothekeoma and Perineurioma With a Folliculin Gene Mutation

Journal of Cutaneous Pathology, Volume 52, Issue 5, Page 374-378, May 2025.
ABSTRACT Hybrid peripheral nerve sheath tumors (PNSTs) are benign tumors that show features of more than one type of PNST. Benign cutaneous plexiform hybrid tumor of perineurioma and cellular neurothekeoma (BCPHTPCN) is a rare, recently described entity that shows various combinations of histomorphologic and immunophenotypic features of the PNSTs ...
Taylor J. Prechtel, Emma Brashear, Carina A. Dehner, Ahmed K. Alomari   +3 more
wiley   +1 more source

Recurrent GRHL fusions in a subset of sebaceoma: microscopic and molecular characterisation of eight cases

Histopathology, Volume 86, Issue 4, Page 571-584, March 2025.
Morphological features of RCOR1::GRHL2 adnexal tumour (case 4). Aims Sebaceous neoplasms constitute a group of adnexal tumours, including sebaceous adenoma, sebaceoma and sebaceous carcinoma. Although mismatch repair deficiency may be observed, the nature of the genetic alterations contributing to the development of most of these tumours is still ...
Mélanie Legrand, Baptiste Louveau, Nicolas Macagno, Maxence Mancini, Dmitry V Kazakov, Daniel Pissaloux, Franck Tirode, Anne Tallet, Samia Mourah, Quentin Lepiller, Arnaud de la Fouchardière, Pierre Sohier, Eric Frouin, Andreas von Deimling, Keisuke Goto, Bernard Cribier, Eduardo Calonje, Saleem Taibjee, Maxime Battistella, Thibault Kervarrec   +19 more
wiley   +1 more source

Dermatologic symptoms associated with gastrointestinal neoplasia

Przegląd Dermatologiczny, 2017
Gastrointestinal tumors are among the most common neoplastic causes of death worldwide. Presence of characteristic skin lesions can allow faster diagnosis and therapy and this way can increase the probability of a cure.
Beata Młynarczyk-Bonikowska, Jacek Muszyński, Sławomir Majewski   +2 more
doaj   +1 more source

Three Different Primary Cancers, Including Breast, Esophagus, and Renal in a Single Patient: A Case Report

Clinical Case Reports, Volume 13, Issue 2, February 2025.
ABSTRACT There are different combinations of multiple primary cancers; however, the combination of breast, esophagus, and renal cancer has been reported in a few cases. Given the rising prevalence of multiple primary cancers over the past decade, understanding the risk factors for early detection is crucial.
Amir Alinejad Khorram, Mohammad Soleimani, Ali Amani‐Beni, Tahmineh Mollasharifi, Reza Amani‐Beni, Farzad Allameh   +5 more
wiley   +1 more source