Results 91 to 100 of about 1,077,360 (248)

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett, Abigail Dubois, Melanie Leguizamon, Alexander Song, Paula Trujillo, Colin D. McKnight, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen   +8 more
wiley   +1 more source

A Prospective Study of Individuals at Risk of Multiple Sclerosis Informs the Design of Primary Prevention Studies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen, Ceren Tozlu, Tina Roostaei, Fatoumata Diallo, Kaho Onomichi, Jiyeon Son, Zongqi Xia, Philip L. De Jager   +7 more
wiley   +1 more source

Agent-Based Participatory Simulations: Merging Multi-Agent Systems and Role-Playing Games [PDF]

In 2001, Olivier Barreteau proposed to jointly use multi-agent systems and role-playing games for purposes of research, training and negotiation support in the field of renewable resource management.
Paul Guyot, Shinichi Honiden
core  

A Systematic Comparison of Alpha‐Synuclein Seed Amplification Assays for Increasing Reproducibility

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Seed amplification assays (SAAs) enable ultrasensitive detection of misfolded α‐synuclein across biofluids and tissues. Yet, heterogeneity in protocols limits cross‐study comparability and clinical translation. Here, we review α‐synuclein SAA methods and their performance across various biological matrices.
Manuela Amaral‐do‐Nascimento, Daniela F. Santos, Tuane C. R. G. Vieira, Tiago F. Outeiro   +3 more
wiley   +1 more source

An adaptive neural design for planar rigid formation of three coleaders in unknown flowfields

IET Control Theory & Applications
This article deals with the robust planar rigid formation control problem of three second‐order coleaders with unknown flowfields acting on the velocity and acceleration respectively.
Weibin Chen, Peng Xu, Yang‐Yang Chen
doaj   +1 more source

Cooperative Game Theory within Multi-Agent Systems for Systems Scheduling [PDF]

, 2004
Research concerning organization and coordination within multi-agent systems continues to draw from a variety of architectures and methodologies. The work presented in this paper combines techniques from game theory and multi-agent systems to produce ...
Messie, Derek, Oh, Jae C.
core   +3 more sources

Advancing Age Modulates Associations Between Cognitive Impairment and Brain Volumes in Early MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Cognitive impairment is common in multiple sclerosis (MS), but manifestations following the first demyelinating event are relatively unexplored. We investigated cross‐sectional associations between magnetic resonance imaging (MRI)–derived brain volumes and the presence of cognitive impairment outcomes five years after the first ...
Piriyankan Ananthavarathan, Marco Pitteri, Michael Foster, Sara Collorone, Sara Salama, Elisa Colato, Ferran Prados, Baris Kanber, Marios Yiannakas, Claudia A. M. Gandini Wheeler‐Kingshott, Indran Davagnanam, Frederik Barkhof, Declan Chard, Olga Ciccarelli, Ahmed Toosy   +14 more
wiley   +1 more source

Cyber‐physical system model based on multi‐agent system

IET Cyber-Physical Systems
Integrating physical processes with computational components creates cyber‐physical systems (CPS) that seamlessly interact between the physical and digital worlds.
Maqbol Ahmed, Okba Kazar, Saad Harous
doaj   +1 more source

OPACA: Toward an Open, Language- and Platform-Independent API for Containerized Agents

IEEE Access
While multi-agent frameworks can provide many advanced features, they often suffer from not being able to seamlessly interact with the outside world, e.g., with web-services or other multi-agent frameworks.
Benjamin Acar, Tobias Kuster, Oskar F. Kupke, Robert K. Strehlow, Marc Guerreiro Augusto, Fikret Sivrikaya, Sahin Albayrak   +6 more
doaj   +1 more source

On stability and controllability of multi-agent linear systems [PDF]

, 2016
Recent advances in communication and computing have made the control and coordination of dynamic network agents to become an area of multidisciplinary research at the intersection of the theory of control systems, communication and linear algebra.
García Planas, María Isabel, Tarragona, Sonia   +1 more
core   +1 more source