Results 81 to 90 of about 39,694 (292)
A Multi-Critic Reinforcement Learning Method: An Application to Multi-Tank Water Systems
IEEE Access, 2020 This paper investigates the combination of reinforcement learning and neural networks applied to the data-driven control of dynamical systems. In particular, we propose a multi-critic actor-critic architecture that eases the value function learning task ...
Juan Martinez-Piazuelo +3 more
doaj +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
The Master model on multi-actor and multilevel social responsibilities [PDF]
, 2011 This working paper contributes to a collective discussion in a workshop occurring in January 2011 at the International Institute of Social Studies, bringing scholars from Europe and Brazil and aiming inter-university research collaboration on linking ...
Ashley, P.A. (Patricia Almeida)
core
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Perspective study: governance for C2C [PDF]
, 2010 This perspective study will serve as frame of reference for follow-up activities and exchanges both within and outside the Cradle to Cradle Network (C2CN) and it aims to reflect the current challenges and opportunities associated with implementing a ...
Dewulf, A., Hovelynck, J., Sips, K.
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Analisis Peran Multi Aktor Dalam Implementasi Kebijakan Minapolitan Berbasis Sustainable Development (Studi Pada Pilot Project Minapolitan Desa Srowo Kecamatan Sidayu Gresik) [PDF]
, 2013 Based on the minister of marine and fisheries No. 35 of 2010 established as the Minapolitan and implemented in the Srowo village, Sidayu sub-district.Implementation Minapolitan have a positive impact on the economy.However, these policies also have a ...
Ulum, S. (Saiful)
core
Parameterized Concurrent Multi-Party Session Types
, 2012 Session types have been proposed as a means of statically verifying implementations of communication protocols. Although prior work has been successful in verifying some classes of protocols, it does not cope well with parameterized, multi-actor ...
Agha, Gul +2 more
core +2 more sources
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
The EU Water Initiative at 15: Origins, Processes and Assessment [PDF]
, 2017 This article examines the activities and achievements of the European Union Water Initiative, a transnational, multi-actor partnership established in 2002 by the European Commission to support water governance reforms around the world.
Adelle, C, Benson, D, Fritsch, O
core +2 more sources