Results 81 to 90 of about 1,068,325 (276)

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

Multi Agent Systems

open access: yesInternational Journal For Multidisciplinary Research
The dominant paradigm of the modern internet, built on graphical user interfaces (GUIs) and discrete web applications, forces users into a fragmented and manual process of interaction, fundamentally limiting the complexity of tasks that can be automated.
Manav Manoj, Vishnu Mohan C -
openaire   +2 more sources

Bridging the Gap between ABM and MAS: A Disaster-Rescue Simulation Using Jason and NetLogo

open access: yesComputers, 2018
An agent is an autonomous computer system situated in an environment to fulfill a design objective. Multi-Agent Systems aim to solve problems in a flexible and robust way by assembling sets of agents interacting in cooperative or competitive ways for the
Wulfrano Arturo Luna-Ramirez   +1 more
doaj   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

Agent-Based Participatory Simulations: Merging Multi-Agent Systems and Role-Playing Games [PDF]

open access: yes
In 2001, Olivier Barreteau proposed to jointly use multi-agent systems and role-playing games for purposes of research, training and negotiation support in the field of renewable resource management.
Paul Guyot, Shinichi Honiden
core  

Cooperative Game Theory within Multi-Agent Systems for Systems Scheduling [PDF]

open access: yes, 2004
Research concerning organization and coordination within multi-agent systems continues to draw from a variety of architectures and methodologies. The work presented in this paper combines techniques from game theory and multi-agent systems to produce ...
Messie, Derek, Oh, Jae C.
core   +3 more sources

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

open access: yesAging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef   +2 more
wiley   +1 more source

OPACA: Toward an Open, Language- and Platform-Independent API for Containerized Agents

open access: yesIEEE Access
While multi-agent frameworks can provide many advanced features, they often suffer from not being able to seamlessly interact with the outside world, e.g., with web-services or other multi-agent frameworks.
Benjamin Acar   +6 more
doaj   +1 more source

Human-AI collaboration in Hybrid Multi-Agent Systems [PDF]

open access: yesInternational Journal of Electronics and Telecommunications
This paper examines Hybrid Multi-Agent Systems, integrating both human and non-human intelligent agents, as a new subject of management research. It presents original definitions of key concepts: intelligent agents, artificial intelligent agents, and ...
Rafal Labedzki
doaj   +1 more source

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