Results 91 to 100 of about 483,640 (297)

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Dominance Measuring Approach using Stochastic Weights

open access: yes, 2010
In this paper we propose an approach to obtain a ranking of alternatives in multicriteria decision-making problems when there is imprecision concerning the alternative performances, component utility functions and weights.
Aguayo Garcia, Ernesto Aaron   +3 more
core  

Ranking Alternatives on the Basis of the Intensity of Dominance and Fuzzy Logic within MAUT [PDF]

open access: yes, 2010
We introduce dominance measuring methods to derive a ranking of alternatives to deal with incomplete information in multi-criteria decision making problems on the basis of Multi-Attribute Utility Theory (MAUT).
Jiménez Martín, Antonio   +2 more
core   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Multicriteria Modelling of Irrigation Water Market at Basin Level [PDF]

open access: yes
This paper develops a multi-criteria methodology to simulate irrigation water markets at basin level. For this purpose it is assumed that irrigators try to optimise personal multi-attribute utility functions via their productive decision making process ...
José A. Gómez-Limón   +1 more
core  

Intelligent protocol adaptation for enhanced medical e-collaboration [PDF]

open access: yes, 2003
Copyright @ 2003 AAAIDistributed multimedia e-health applications have a set specific requirements which must be taken into account effective use is to be made of the limited resources provided by public telecommunication networks.
Frank, AO, Ghinea, G, Magoulas, GD
core  

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Development of Decision Support System Determining the Student as Scholarship Recipients by Fuzzy Multi Attribute Decision Making (Fmadm) [PDF]

open access: yes, 2013
This research is the design of a decision support system (DSS) to determining the student as scholarship recipients of the STMIK Pelita Nusantara, Medan, Indonesia, with the approach of Fuzzy Multi Attribute Decision Making (FMADM) with TOPSIS method ...
Marbun, M. (Murni)   +2 more
core  

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

open access: yesFEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão   +3 more
wiley   +1 more source

Sensitivity Analysis of TOPSIS Technique: The Results of Change in the Weight of One Attribute on the Final Ranking of Alternatives [PDF]

open access: yesJournal of Optimization in Industrial Engineering, 2011
Most of data in Multi-attribute decision making (MADM) problems are changeable rather than constant and stable. Therefore, sensitivity analysis after problem solving can effectively contribute to making accurate decisions.
Alireza Alinezhad, Abbas Amini
doaj  

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