Results 91 to 100 of about 121,475 (299)

Exemplar-based inference in multi-attribute decision making [PDF]

open access: yesJudgment and Decision Making, 2008
Several studies propose that exemplar retrieval contributes to multi-attribute decisions. The authors have proposed a process theory enabling a priori predictions of what cognitive representations people use as input to their judgment process (extit ...
Linnea Karlsson   +2 more
doaj  

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Multi-Attribute Decision-Making Model by Applying Grey Numbers

open access: yesInformatica, 2009
Multi-attribute analysis is a useful tool in many economical, managerial, constructional, etc. problems. The accuracy of performance measures in COPRAS (The multi-attribute COmplex PRoportional ASsessment of alternatives) method is usually assumed to be accurate. This method assumes direct and proportional dependence of the weight and utility degree of
Zavadskas, Edmundas Kazimieras   +3 more
openaire   +3 more sources

Astrocyte heterogeneity in brain metastases

open access: yesMolecular Oncology, EarlyView.
Astrocytes emerge as pivotal regulators of metastatic colonization, survival, immune remodeling, and therapy response associated with an increasing heterogeneity that requires spatially and longitudinally resolved approaches to uncover regulatory programs and guide context‐specific therapies.
Carolina Hernández‐Oliver   +2 more
wiley   +1 more source

From tumor‐centric to ecosystem‐based hypotheses in brain tumor research and care

open access: yesMolecular Oncology, EarlyView.
Primary brain tumors, whether in adults or children, present a major challenge because of their dramatic prognosis and the ongoing lack of efficient therapeutic approaches. In recent years, a shift has occurred from tumor‐centric concepts to a more holistic view of these tumors as dynamic ecosystems.
Julie Gavard   +8 more
wiley   +1 more source

Decision-making Strategies and Performance among Seniors [PDF]

open access: yes
Using paper and pencil experiments administered in senior centers, we examine decision-making performance in multi-attribute decision problems. We find a significant decline in performance with age due to reduced reliance on common heuristics among our ...
Mikhael Shor   +3 more
core  

Multi-attribute Decision Making Based on Z-valuation [PDF]

open access: yes, 2016
In this paper we investigate multi-attribute decision making problem, where the attribute values are Z-numbers, and the weight information on attributes are partially reliable. The presented method is based on overall criteria positive ideal and negative
Aliyev, Rafig R.
core   +1 more source

Multi-Attribute Group-Decision on a Construction Diversion Scheme for Hydropower Projects Based on Perception Utility

open access: yesEnergies, 2018
The multi-attribute and group-decision problem in the selection of a construction diversion scheme for large hydropower projects often involves multi-decision subjects and schemes.
Dawei Liu, Zhigen Hu, Wencheng Guo
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

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