Multi-body modelling and adaptive control of a re-configurable uninhabited airship
This paper presents pitch control of an uninhabited airship using changes in center of gravity. Changes in center of gravity are achieved by controlling the position of a movable gondola along a rigid keel fixed to the bow of the helium envelope.
Gilmar Tuta-Navajas, Eric Lanteigne
doaj +1 more source
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Advanced Multi-Body Modelling of DCCSS Isolators: Geometrical Compatibility and Kinematics
The effectiveness of Double Concave Curved Surface Sliders (DCCSS), which initially spread under the name of Double Friction Pendulum (DFP) isolators, was already widely proven by numerous experimental campaigns carried out worldwide.
Vincenzo Bianco +2 more
doaj +1 more source
Acoustic manipulation of multi-body structures and dynamics
Abstract Sound can exert forces on objects of any material and shape. This has made the contactless manipulation of objects by intense ultrasound a fascinating area of research with wide-ranging applications. While much is understood for acoustic forcing of individual objects, sound-mediated interactions among multiple objects at close ...
Melody X Lim +2 more
openaire +3 more sources
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Multi-body Dynamics Simulation of Timing Belt Drive System for Automotive Engine based on RecurDyn
Based on the multi-body dynamics software RecurDyn, combined with the layout design parameters of a gasoline engine timing belt drive system, the multi-body dynamics simulation model of the timing belt drive system is established. Through theoretical and
Zengming Feng, Jinxing Yang
doaj
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Integrated FEM-Multibody Co-Simulation of Additively Manufactured Hip Prosthesis containing cracks
The increase in life expectancy and attention to the quality of life of elderly people spurred the need, in the last decades, to increase the capabilities of medical and surgical techniques.
Roberto Di Bona +4 more
doaj +1 more source

