Results 41 to 50 of about 9,433,404 (275)
Multi-body Dynamics Study of Gears [PDF]
, 2022 Gear faults can usually occur due to fatigue, spalling or pitting caused by wear, load fluctuations, backlash etc. This severely reduces actual strength of the gears and prompts crack growth. Fatigue cracks may appear in the region of highest stresses, whose location can be determined based on numerical analysis, meshing force variability, point of ...
openaire +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
The effects of surface compliance on greyhound galloping dynamics [PDF]
, 2019 © IMechE 2019. Greyhounds are the fastest breed of dog and can reach a speed up to 68 km/h. These racing animals sustain unique injuries seldom seen in other breeds of dog.
Hayati, H, Walker, P, Eager, D
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Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Analysis of free-field pressure sensor laying mechanism design in anti-shock test of warship
Zhongguo Jianchuan Yanjiu, 2019 [Objectives]In order to solve the problem of free-field pressure sensor laying in dynamic anti-shock test of warship,[Methods]based on the theory of computational multi-body dynamics and fluid dynamics,the laying mechanism of free-field pressure sensor ...
Gao Haopeng
doaj +1 more source
Numerical study of railway wheel wear on roller rigs
Nihon Kikai Gakkai ronbunshu, 2020 The dynamic behavior of railway vehicle is often tested by roller rig equipment and this test is very useful. However, it is known that contact condition on roller rig is different from the case that wheels run on rail.
Satoshi HARA +3 more
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Multi-body dynamics simulation of geometrically exact Cosserat rods
, 2022 S.285-312In this paper, we present a viscoelastic rod model that is suitable for fast and accurate dynamic simulations. It is based on Cosserats geometrically exact theory of rods and is able to represent extension, shearing (stiff dof), bending and ...
Lang, H., Linn, J., Arnold, M.
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FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
‘Guide and Prejudice’— How Argonautes recognize targets across domains of life
FEBS Letters, EarlyView.Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley +1 more source
A Vector Bond Graph Method of Dynamics Modeling for Planar Multi-body Systems with Grooved Sheave
Jixie chuandong, 2017 In order to increase the reliability and efficiency of the dynamics modeling and analysis for complex planar multi-body systems containing grooved sheave,the corresponding vector bond graph procedure is proposed.
Wang Zhongshuang +2 more
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