Results 51 to 60 of about 9,433,404 (275)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Variational multirate integration in multi‐body dynamics [PDF]
PAMM, 2016 AbstractFor systems that contain slow and fast dynamics, variational multirate integration schemes are used. These schemes split the system into parts which are simulated using two time grids consisting of micro and macro nodes. This formulation can be extended for multi‐body systems.
Tobias Gail +2 more
openaire +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
LubricantsTraditional revolute clearance joints assume that the shape of the contact surface of the joint is regular and ignores the effects of wear, which reduces the prediction accuracy of dynamics models.
Yonghao Jia +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
MULTI-BODY SIMULATIONS OF RAILWAY WAGON DYNAMICS
Journal of KONES. Powertrain and Transport, 2015 The main aim of the presented paper is to verify the dynamics of chosen railway wagon using multi-body methods. Thus, in tests a wagon prototype with rotational rail-car body was simulated, which is going to be used for TIR vehicles trailer bodies transporting.
Krzysztof Wójcik +5 more
openaire +1 more source
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Jixie chuandong, 2018 In order to study the influence of modification of cycloid gear and bearing clearance on angular transmission error of RV reducer,based on the multi-body dynamics simulation technology,multi-body contact between gears is established by combining with the
Chang Anquan +3 more
doaj
Mechanics & IndustryIn this study, free high-level programming languages, GNU Octave and Python, are used to model the mechanical part simulating the periodic signal generated in the mechanical system and to link with the signal processing unit that analyzes the generated ...
Park Yonghu
doaj +1 more source
Development of Real-time Remote Driving Simulator based on Multi-body Dynamics [PDF]
한국정밀공학회지Autonomous robots are commonly operated on rough roads. Thus, it is essential to predict their dynamic characteristics. Even though it is possible to use real hardware to acquire a robot’s dynamic characteristics, this requires a significant amount of ...
Suhyun Park +2 more
doaj +1 more source