Results 41 to 50 of about 1,363,648 (272)

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

open access: yesMolecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard   +12 more
wiley   +1 more source

Organic farming and multicriteria decisions: An economic survey [PDF]

open access: yes, 2012
Organic food production is a sphere where decision making is multi-facetted and complex. This applies to producers, political decision makers and consumers alike.
Christensen, Tove   +3 more
core  

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

Multi-Criteria Decision Making (MCDM) Methods and Concepts

open access: yesEncyclopedia, 2023
Multi-criteria decision-making (MCDM) is one of the main decision-making problems which aims to determine the best alternative by considering more than one criterion in the selection process.
Hamed Taherdoost, Mitra Madanchian
doaj   +1 more source

The intuitionistic fuzzy multi-criteria decision making based on inclusion degree [PDF]

open access: yes, 2017
This paper introduces a new intuitionistic fuzzy multicriteria decision making method of evaluation based on degree of inclusion of two intuitionistic fuzzy sets.
Ashraf, Samina   +2 more
core   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

Validating a Multi-criteria decision analysis (MCDA) framework for health care decision making (abstract) [PDF]

open access: yes, 2011
OBJECTIVES: When evaluating healthcare interventions, decision-makers are increasingly asked to consider multiple criteria to support their decision. The MCDA-based EVIDEM framework was developed to support this process.
Dolan, J.G.   +4 more
core   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Penggunaan Algoritma Multi Criteria Decision Making dengan Metode Topsis dalam Penempatan Karyawan

open access: yesJurnal EECCIS (Electrics, Electronics, Communications, Controls, Informatics, Systems), 2015
The employees are a major asset in the company so that the company can operate properly. In employees pacement, often a mismatch between the positions of the competence of employees.
Agung N. Pramudhita   +2 more
doaj   +1 more source

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