Molecular Epidemiology of the <i>bla</i><sub>CTX-M</sub> Gene in <i>Escherichia coli</i> from a Pig Farm: Antimicrobial Resistance Profiles, Genetic Background, and Its Horizontal Transfer and Environmental Dissemination. [PDF]
MicroorganismsJiang RH +5 more
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Diagnosis of Multi-Drug Resistant (MDR) tuberculosis in the Democratic Republic of the Congo [PDF]
, 2018 openaire
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AmpC Inhibition: An Explicit Approach against Multi-Drug Resistance (MDR)
Current Topics in Medicinal Chemistry, 2023Abstract:Multi-drug resistance and its transmission is a ubiquitous health issue worldwide. The beta-lactamase AmpC resistance is a major concern among all health settings like hospitals and child care centers, etc. The clinical pipeline of the new antibiotics remains dry due to the production of AmpC beta-lactamases by the bacteria to develop ...
Akash Jain, Jasmine Chaudhary
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Abnormal saccharides affecting cancer multi-drug resistance (MDR) and the reversal strategies
European Journal of Medicinal Chemistry, 2021Clinically, chemotherapy is the mainstay in the treatment of multiple cancers. However, highly adaptable and activated survival signaling pathways of cancer cells readily emerge after long exposure to chemotherapeutics drugs, resulting in multi-drug resistance (MDR) and treatment failure.
Jiliang Hu, Bangxing Han, Yahui Huang
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Screening and cloning of multi-drug resistant genes in HL-60/MDR cells
Leukemia Research, 2009To screen and clone multi-drug resistance (MDR) related genes in MDR acute myeloid leukemia cells (HL-60/MDR).HL-60/MDR was established using All-Trans Retinoic Acid. With the HL-60 cells as "tester" and HL60/MDR as "driver", the cDNA library of HL-60/MDR was established by suppression subtractive hybridization. Then 12 of the resulting subtracted cDNA
Jian-Feng Zhou
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Multi-drug resistance tuberculosis (MDR-TB) in Kassala State, Eastern Sudan
Tropical Doctor, 2013This study investigates the prevalence of drug resistance and mutations in rpoB gene among Mycobacterium tuberculosis isolates from Kassala State, Sudan. In a cross-sectional study during 2011, sputum specimens ( n = 90) were examined microscopically and grown cultures were identified by analysing IS6110 insertion sequence.
Ahmed A, Abdul-Aziz +4 more
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Molecular Analysis of Multi-Drug Resistance (MDR) in Mycobacterium tuberculosis
Journal of Medical Laboratory Science, 2009The recent emergence of multi-drug resistant (MDR) strains of Mycobacterium tuberculosis has become an area of great concern. This occurs as a result of inadequate treatment management of tuberculosis which provides a selectivepressure that favours the emergence of resistant mutants with enhanced infectiousness.
Umo, AM, Udo, SM
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Multi Drug Resistant Tuberculosis (MDR-TB)
North East Medical College Journal, 2015Introduction: Tuberculosis (TB) is prevalent throughout the world, which is caused by bacteria; usually affects the lungs, but can also affect other parts of the body (brain, kidneys, intestine, skin and bone), which is treatable and curable. But, it is difficult to treat the Drug Resistant tuberculosis (DR-TB).
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