Results 31 to 40 of about 46,954 (256)

Genome-wide dissection of globally emergent multi-drug resistant serotype 19A Streptococcus pneumoniae

BMC Genomics, 2009
Background Emergence of multi-drug resistant (MDR) serotype 19A Streptococcus pneumoniae (SPN) is well-documented but causal factors remain unclear. Canadian SPN isolates (1993-2008, n = 11,083) were serotyped and in vitro susceptibility tested. A subset
Wong Andrew, Khairnar Krishna, Lau Rachel, Pollock Remy A, Buzina Alla, Shahinas Dea, Pillai Dylan R, Farrell David J, Green Karen, McGeer Allison, Low Donald E   +10 more
doaj   +1 more source

The prevalences of Salmonella Genomic Island 1 variants in human and animal Salmonella Typhimurium DT104 are distinguishable using a Bayesian approach [PDF]

, 2011
Throughout the 1990s, there was an epidemic of multidrug resistant Salmonella Typhimurium DT104 in both animals and humans in Scotland. The use of antimicrobials in agriculture is often cited as a major source of antimicrobial resistance in pathogenic ...
Matthew J Denwood, Reid, S W J, Derek J Brown, Daniel T Haydon, Mellor Dominic J., Mellor, D J, Louise Matthews, Alison E. Mather, Matthews, L., Reid Stuart W. J., Mather, A E, Haydon, D T, Derek J. Brown, Alison E Mather, John E Coia, Coia John E., Matthews, L, Mather, A.E., Stuart W J Reid, Daniel T. Haydon, Brown, D J, Denwood Matthew J., Haydon, D.T., Coia, J E, Dominic J. Mellor, Brown Derek J., John E. Coia, Coia, J.E., Reid, S.W.J., Matthew J. Denwood, Matthews Louise, Stuart W. J. Reid, Denwood, M.J., Denwood, M J, Mather Alison E., Mellor, D.J., Dominic J Mellor, Haydon Daniel T., Brown, D.J.   +38 more
core   +1 more source

Phenotypic and Genotypic Characterization of Multi-Drug Resistant Mycobacterium tuberculosis

UMYU Journal of Microbiology Research, 2020
This study characterized multi-drug resistant M. tuberculosis phenotypically by LJ-proportion method and genotypically by GenoType MTBDRplus LPA. Out of the forty M.
Aliyu, M. S., Garba, I., Tijjani, M. B., Doko, M. H .I., Mukhtar, G. L., Musa, B., Madika, A.   +6 more
doaj   +1 more source

Inhibition of ABCB1 (MDR1) expression by an siRNA nanoparticulate delivery system to overcome drug resistance in osteosarcoma. [PDF]

PLoS ONE, 2010
The use of neo-adjuvant chemotherapy in treating osteosarcoma has improved patients' average 5 year survival rate from 20% to 70% in the past 30 years.
Michiro Susa, Arun K Iyer, Keinosuke Ryu, Edwin Choy, Francis J Hornicek, Henry Mankin, Lara Milane, Mansoor M Amiji, Zhenfeng Duan   +8 more
doaj   +1 more source

Advances in BODIPY Derivatives for Antibacterial Phototherapy

Angewandte Chemie, EarlyView.
This review systematically summarizes the design strategies and structure‐activity relationships of BODIPY‐based antibacterial phototherapy, covering molecular engineering of small‐molecule photosensitizers and nanoplatforms, bacterial targeting and carrier design, and discussing the challenges and future perspectives associated with clinical ...
Li Lv, Heejeong Kim, Hongchen Zhai, Hanqi Ren, Silu Wang, Cong Sun, Yafu Wang, Hosoowi Lee, Juyoung Yoon, Hua Zhang   +9 more
wiley   +2 more sources

The HIV-1 Reverse Transcriptase A62V Mutation Influences Replication Fidelity and Viral Fitness in the Context of Multi-Drug-Resistant Mutations

Viruses, 2018
Emergence of human immunodeficiency virus type 1 (HIV-1) drug resistance arises from mutation fixation in the viral genome during antiretroviral therapy. Primary mutations directly confer antiviral drug resistance, while secondary mutations arise that do
José O. Maldonado, Louis M. Mansky
doaj   +1 more source

The nuclear membrane in multidrug resistance: microinjection of epirubicin into bladder cancer cell lines

, 2005
Objevtive: to assess whether microinjecting epirubicin into cells showing multidrug resistance (MDR, common to many cancers, including bladder cancer, with resistance to, e.g.
Birch, B.R, Hayes, C.M, Featherstone, J.F, Cooper, A.J, Speers, A.G, Lwaleed, B.A   +5 more
core   +1 more source

Drug resistance-conferring mutations in Mycobacterium tuberculosis from Madang, Papua New Guinea [PDF]

, 2012
: BACKGROUND: Monitoring drug resistance in Mycobacterium tuberculosis is essential to curb the spread of tuberculosis (TB). Unfortunately, drug susceptibility testing is currently not available in Papua New Guinea (PNG) and that impairs TB control in ...
Gagneux, S., Siba Peter, Beck, H. P., Hans-Peter Beck, Beck Hans-Peter, Carter Robyn, Paul Harino, Harino, P., Carter, R., Serej Ley, Ley Serej, Siba, P., Gagneux Sebastien, Borrell Sonia, Coscolla Mireia, Mireia Coscolla, Ballif Marie, Stefan Niemann, Ley, S., Marie Ballif, Coulter, C., Robyn Carter, Coulter Christopher, Christopher Coulter, Ballif, M., Peter Siba, Niemann, S., Harino Paul, Niemann Stefan, Sebastien Gagneux, Phuanukoonnon, S., Borrell, S., Coscolla, M., Sonia Borrell, Suparat Phuanukoonnon, Phuanukoonnon Suparat   +35 more
core   +1 more source

ORIGINAL ARTICLE: Resistance To Quinolones, Aminoglycosides And Capreomycin In Multi Drug Resistant M.Tuberculosis

Pakistan Journal of Medicine and Dentistry, 2022
Background: Tuberculosis is a major health issue of developing countries like Pakistan. Multi drug resistance (MDR) and Extensive drug resistance (XDR) in M. tuberculosis is on continuous rise in our region.
Samia Khanam, Rabia Arshad, Muhammad Adnan Kanpurwala, Sobia Hasan, Fakhur uddin, Mohammad Asif Durrani   +5 more
doaj  

Predictor of multidrug resistant tuberculosis in southwestern part of Ethiopia: a case control study

Annals of Clinical Microbiology and Antimicrobials, 2018
Background Curable disease tuberculosis is becoming incurable or difficult to treat due to drug resistance. Multi drug resistance tuberculosis is a major health problem for less developed countries.
Dabesa Gobena, Gemechu Ameya, Kinfe Haile, Getaneh Abreha, Yoseph Worku, Tessema Debela   +5 more
doaj   +1 more source