Results 101 to 110 of about 79,223 (384)

Immunoinformatics approach to designing a multi-epitope vaccine against Saint Louis Encephalitis Virus

Informatics in Medicine Unlocked, 2021
The Saint Louis Encephalitis Virus (SLEV) is one of the causes of a rare, inflammatory condition of the brain tissues known as encephalitis. Belonging to the Flaviviridae family, SLEV can cause severe, detrimental repercussions on the central nervous ...
Md. Shakhawat Hossain, Mohammad Imran Hossan, Shagufta Mizan, Abu Tayab Moin, Farhana Yasmin, Al-Shahriar Akash, Shams Nur Powshi, A.K Rafeul Hasan, Afrin Sultana Chowdhury   +8 more
doaj   +1 more source

CD8+ T-cell responses in vaccination: Reconsidering targets and function in the context of chronic antigen stimulation [PDF]

, 2018
Cytotoxic CD8 T cells play important roles in eliminating infected and transformed cells. Owing to their potential for therapeutic applications, significant efforts are dedicated toward developing CD8 T cell-based vaccines.
Cosma, Gabriela L., Eisenlohr, Laurence
core   +2 more sources

A computational immune-informatics approach to design multi-epitope vaccine against Guanarito virus targeting nucleoprotein and nucleo-capsid proteins

World Journal of Biology and Biotechnology
The human Guanarito virus (GTOV), belongs to the order Bunyavirales and family Arenaviradae, was found in the Portuguese state of Portugal’s Guanarito municipality.
I. U. Haq, Najeeb Ullah, M. Rahiyab, Syed Shujait Ali, Ishaq Khan, Zahid Hussain, Arshad Iqbal   +6 more
semanticscholar   +1 more source

A multi-epitope vaccine GILE against Echinococcus Multilocularis infection in mice

Frontiers in Immunology, 2023
Introduction The objective of this study is to construct a multi-epitope vaccine GILE containing B-cell and T-cell epitopes against Echinococcus Multilocularis (E. multilocularis) infection based on the dominant epitopes of E. multilocularis EMY162, LAP,
P. Zhou, Z. Zhou, Meiduo Huayu, Lei Wang, Lin Feng, Yang Xiao, Y. Dai, M. Xin, Feng Tang, Runle Li   +9 more
semanticscholar   +1 more source

Generation of an Induced Pluripotent Stem Cell‐Derived Alveolar Type II In Vitro Model to Study Influenza A Virus Infection and Drug Treatments

Advanced Healthcare Materials, EarlyView.
Patient‐specific induced pluripotent stem cells (iPSCs) can be differentiated into alveolar type II cells (iAT2s), expanded as 3D alveolospheres, and grown at physiologically relevant air–liquid interface (ALI). This study shows for the first time the infectability of iAT2s by the influenza A virus (IAV) and proves their responsiveness to the well ...
Lena Gauthier, Hristina Koceva, Yann Bachelot, Rosanne W. Koutstaal, Puck B. van Kasteren, Marc Thilo Figge, Christian Eggeling, Alexander Sandy Mosig   +7 more
wiley   +1 more source

Systems approach to design multi-epitopic peptide vaccine candidate against fowl adenovirus structural proteins for Gallus gallus domesticus

Frontiers in Cellular and Infection Microbiology
IntroductionFowl adenovirus (FAdV) is a significant pathogen in poultry, causing various diseases such as hepatitis-hydropericardium, inclusion body hepatitis, and gizzard erosion.
Susithra Priyadarhni Mugunthan, Divyadharshini Venkatesan, Chandramohan Govindasamy, Dhivya Selvaraj, Mani Chandra Harish   +4 more
doaj   +1 more source

A bioinformatics approach to introduce novel multi-epitope vaccines against Acinetobacter baumannii retrieved from immunogenic extracellular loops of outer membrane proteins

Informatics in Medicine Unlocked, 2022
Increasing antibiotic resistance of Acinetobacter baumannii highlights the urgent need to develop an effective vaccine to combat it. Despite all efforts, no approved vaccine against this bacterium is on the market, and attempts are underway to find ...
Maryam Meskini, Narjes Noori Goodarzi, Sepideh Fereshteh, Negin Bolourchi, Amir Mirzaie, Farzad Badmasti   +5 more
doaj   +1 more source

Design of multi-epitope vaccine against porcine rotavirus using computational biology and molecular dynamics simulation approaches

Virology Journal
Porcine Rotavirus (PoRV) is a significant pathogen affecting swine-rearing regions globally, presenting a substantial threat to the economic development of the livestock sector.
Xiaochen Zhu, Xinyuan Wang, Tingting Liu, Dongchao Zhang, Tianming Jin   +4 more
semanticscholar   +1 more source

Membrane Fusion‐Inspired Nanomaterials: Emerging Strategies for Infectious Disease and Cancer Diagnostics

Advanced Healthcare Materials, EarlyView.
Membrane fusion‐inspired nanomaterials offer transformative potential in diagnostics by mimicking natural fusion processes to achieve highly sensitive and specific detection of disease biomarkers. This review highlights recent advancements in nanomaterial functionalization strategies, signal amplification systems, and stimuli‐responsive fusion designs,
Sojeong Lee, Khulan Nyamzaya, Jueun Han, Yejin Song, Jihee Lee, Jung Hyun Jo, Seungmin Bang, Eun‐Kyung Lim, Seungjoo Haam, Eunjung Kim   +9 more
wiley   +1 more source

Design of a Multi-epitope Peptide Vaccine against SARS-CoV-2 based on Immunoinformatics Data

Journal of Mazandaran University of Medical Sciences, 2020
Background and purpose: In 2019, the world has witnessed the emergence of a virus that caused acute respiratory distress syndrome in human with high mortality rates (approximately 3.7%).
Alireza Habibi, Amin Azizan, Yahya Ehteshaminia, Farhad Jadidi-Niaragh, Ehsan Enderami, Esmaeil Akbari, Saeid Abediankenari, Hadi Hassannia   +7 more
doaj