Results 271 to 280 of about 36,032 (319)

Clustering of Membrane Receptors: Insights from DNA Origami‐Based Approaches

Small, EarlyView.
Receptor clustering critically influences cell signaling, yet its precise regulation remains elusive. This review highlights how DNA origami structures serve as nanoscale tools to uncover receptor organization and provide new insights into signal transduction.
Carmen M. Domínguez, Christof M. Niemeyer   +1 more
wiley   +1 more source

Immunoinformatic approach to the design of a novel multi-epitope vaccine against Leishmania major fused to human IgG-Fc. [PDF]

Res Pharm Sci
Fadaie M, Shahmoradi Z, Khanahmad H.
europepmc   +1 more source

Rapid and Sensitive Detection of RNA Viruses through Imaging of Marker Molecules Derived from Designed Circular DNA Probes

Small Methods, EarlyView.
This study presents a rapid and sensitive virus detection method that employs imaging of virus‐specific DNA markers. Utilizing specially designed single‐stranded circular DNA probes, this method captures RNA fragments from RNase‐digested viral genomes during the reverse transcriptase‐based reaction, resulting in double‐stranded markers that are ...
Yoon‐ha Jang, Taesoo Kim, Su‐jin Hong, Se‐yeon Kim, Hyeseung Hwang, Siwon Kim, Su‐a Kang, Nabin Won, Dogeun Kim, Min Jae Kim, Yong Pil Chong, Seongsoo Jang, Kyubong Jo, Kwang‐il Lim   +13 more
wiley   +1 more source

Computationally designed multi-epitope vaccine construct targeting the SARS-CoV-2 spike protein elicits robust immune responses in silico. [PDF]

Sci Rep
Deepthi V, Sasikumar A, Mohanakumar KP, Rajamma U.   +3 more
europepmc   +1 more source

Fabrication of Microneedles by Pulsating In Situ Dried Electrostretching for Transdermal Drug Delivery

Small Methods, EarlyView.
The pulsating in situ dried electrostretching (PIDES) technique offers a novel approach to microneedles fabrication for transdermal drug delivery utilizing electrohydrodynamic principles. PIDES is capable of fabricating biodegradable polymeric microneedles with geometric and mechanical properties suitable for skin penetration. Drug loading and in vitro
Ngoc Luan Mai, Yuen Yong, Thi Van Anh Hoang, Trung Hieu Vu, Hoai‐Duc Vu, Van Canh Doan, Donglin Cai, Thien Xuan Dinh, Dzung Viet Dao, Van Thanh Dau   +9 more
wiley   +1 more source

Design, Development and Immunogenicity Study of a Multi-Epitope Vaccine Prototype Against SARS-CoV-2. [PDF]

Pharmaceuticals (Basel)
Atanasova M, Dimitrov I, Ralchev N, Markovski A, Manoylov I, Bradyanova S, Mihaylova N, Tchorbanov A, Doytchinova I.   +8 more
europepmc   +1 more source

Analyzing DNA Origami Nanostructure Assembly by Dynamic Light Scattering and Nanoparticle Tracking Analysis

Small Methods, EarlyView.
This figure illustrates the size distribution analysis of reconfigurable DNA nanocages using NTA. It displays three distinct peaks corresponding to particle populations at 43 nm, 73 nm, and 138 nm, each associated with unique nanocage conformations captured by AFMin the insets.
Qiaochu Zhang, Xu Chang, Alireza Ebrahimimojarad, Akshay Shah, Fei Zhang, Jinglin Fu   +5 more
wiley   +1 more source

Designing of an efficient DC-inducing multi-epitope vaccine against Epstein Barr virus targeting the GP350 using immunoinformatics and molecular dynamic simulation. [PDF]

Biochem Biophys Rep
Fatahi G, Abdollahi M, Nashtahosseini Z, Minoo S, Mostafavi M, Saeidi K.   +5 more
europepmc   +1 more source

The regulatory effects and applications of TIGIT/CD155 on the tumor microenvironment in HCC

VIEW, EarlyView.
Background The interaction between TIGIT and CD155 compromises immune cell efficacy in tumor targeting, potentially driving hepatocellular carcinoma (HCC) progression through diverse molecular pathways. What Was Done This study investigates the interplay between CD155 and TIGIT in regulating CD8+ T cell function and elucidates its implications in HCC ...
Wenting Li, Yukun Li, Yao Li, Mingqi Yang, Haichuan Peng, Hongwei Sun, Ping Jiang, Yizhun Zhu, Qiang Chen, Xiaobing Duan, Wei Zhao   +10 more
wiley   +1 more source

A Universal Multi-Epitope Vaccine Design Against Porcine Reproductive and Respiratory Syndrome Virus via Bioinformatics and Immunoinformatics Approaches. [PDF]

Vet Sci
Lei X, Wu Z, Feng Q, Jia W, Xie J, Zhou Q, Ban J, Zhu S.   +7 more
europepmc   +1 more source