Results 121 to 130 of about 5,820,721 (304)

Focus Productions Kramer

, 2013
Kramer Electronics exhibition stand by Focus Productions Pty Ltd (Brisbane)
Focus Productions
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Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Annual Report (Focus on the Global South)

, 2015
The march towards rapid economic growth by Asian states continued throughout 2015 with the development of large infrastructure projects, negotiations around regional and bilateral free-trade agreements and courting of private investment, often at the ...
Focus on the Global Socuth (Program)
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1st International Conference on Innovation and Sustainability: April 3-4 [PDF]

, 2013
The conference, hosted by Universiti Utara Malaysia, will address the relationship between government, industry, the community and the academy in building an open, innovative society and a sustainable economy for the 21st ...
Malaysia, Focus
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Multi-Focus Image Fusion for Full-Field Optical Angiography. [PDF]

Entropy (Basel), 2023
Jie Y, Li X, Wang M, Tan H.
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

The drug problem - this is our fight [PDF]

, 2017
IT IS shocking to hear thai last year, the National Anti-Drug Agency recorded a total of 30,847 drug addicts compared to 26,668 in 2015. The number of new addicts increased from 20,281 to 22,925.It is estimated that currently Malaysia produces an average
Focus, Malaysia
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In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Multi-focus averaging for multiple scattering suppression in optical coherence tomography. [PDF]

Biomed Opt Express, 2023
Zhu L, Makita S, Tamaoki J, Lichtenegger A, Lim Y, Zhu Y, Kobayashi M, Yasuno Y.   +7 more
europepmc   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source