Results 121 to 130 of about 13,022,574 (257)

COMBINING MULTI-LEVEL AND NETWORK GOVERNANCE WITH A SPILLOVER EFFECT: THE CASE OF THE EUROPEAN “INNOVATION UNION” FLAGSHIP INITIATIVE [PDF]

open access: yesChallenges of the Knowledge Society, 2011
The purpose of this paper is to demonstrate the possibility of a theoretical up-grade to the framework offered by the theory of governance: from a middle-range theory to a full theory through adding a neofunctionalist component that would enhance its ...
OANA-ANDREEA ION, IOANA DODI, ANDRA POPA
doaj  

Dactolisib outperforms Rapamycin in potentiating apoptosis induced by XPO1, Bcl‐2 and Mcl‐1 blockade in preclinical glioblastoma models

open access: yesFEBS Open Bio, EarlyView.
The PAM pathway and its impact on cellular metabolism. Color‐coded key symbols represent Rapamycin (R, orange, targeting mTOR) and Dactolisib (D, green, targeting PI3K/mTOR), indicating their sites of action. Created with BioRenders.com. Glioblastoma resists therapy through interconnected survival programs.
Kai Zhao   +23 more
wiley   +1 more source

City Networking in Europe Rescaling of the state and increased importance of cities in the multi-level system of governance [PDF]

open access: yes, 2013
This thesis analyzes city networking from a rescaling perspective, highlighting the shift from government towards non-hierarchical governance, a development shifting political power between different scales.
Delsing, Mimmi
core   +1 more source

Implications of the EU Multi-Level Governance in the Field of Competition Policy – A Comparative Analysis of the Characteristics of Cohesion and Competition Policies [PDF]

open access: yesRomanian Journal of European Affairs, 2011
The paper aims at analyzing the intrinsic characteristics of the European Union and to show that these characteristics objectively require the implementation of multi-level governance.
Florin Bonciu
doaj  

Design and evaluation of FEBS Education and Training Academy module – Integrating generative artificial intelligence into life‐science education

open access: yesFEBS Open Bio, EarlyView.
Life‐science educators from 14 countries redesigned their own course materials with generative AI in a three‐session, pedagogy‐first FEBS Education and Training Academy workshop built on PICRAT. Among 12 matched respondents, four more reported high confidence in each of five practical domains, and 10 of 13 reported implementing at least one idea ...
Zvonimir Mlinarić, Ali Burak Özkaya
wiley   +1 more source

Hydrogel platforms for 3D cardiac tissue engineering and fibrotic disease modelling

open access: yesFEBS Open Bio, EarlyView.
Hydrogel‐based cardiac tissue models are advancing our understanding of heart health and disease. By incorporating electrical conductivity, aligned structures, and tunable mechanical properties, these platforms better replicate the complex environment of native heart tissue.
Harrison Porritt   +2 more
wiley   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Local and global in the governing process: a complex phenomenon

open access: yesSfera Politicii, 2015
In the context of intensive globalization, scientific research in the field of social sciences proposes an explanatory multi- level perspective of the studied phenomena. A key concept belonging to political sciences, yet trans-disciplinarily, is that of „
Emilia‑Elena Clucerescu (Tănase)
doaj  

Governing Integration Policies in a Multi-Level Setting: Austria and Czechia Compared

open access: yesCentral and Eastern European Migration Review
In migration studies, scholars differ in their emphasis on which level of government plays the central role in immigrant integration policies. There are voices drawing attention to a ‘local turn’, highlighting the rising power of local actors in ...
Anna Lukešová
doaj   +1 more source

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