ABSTRACT Introduction Spinal cord infarction (SCI) is a rare but devastating myelopathy, characterized by a high disability rate and an unfavorable prognosis. It has often been underdiagnosed and misdiagnosed as idiopathic transverse myelitis (ITM). This study aimed to describe the clinical features, radiological biomarkers, treatments, and functional ...
Zeqiang Ji +13 more
wiley +1 more source
Governing Integration Policies in a Multi-Level Setting: Austria and Czechia Compared
In migration studies, scholars differ in their emphasis on which level of government plays the central role in immigrant integration policies. There are voices drawing attention to a ‘local turn’, highlighting the rising power of local actors in ...
Anna Lukešová
doaj +1 more source
Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende +26 more
wiley +1 more source
EU transport infrastructure policy, new institutionalism and types of multi-level governance : the cases of Vienna and London [PDF]
The European integration process has fundamentally changed the system of governing in Europe. No longer is European governance confined to the nation-state level, but rather involves a variety of supranational, national and sub-national actors.
Awesti, Anil
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Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett +8 more
wiley +1 more source
Europeanisation at the Urban Level: Local Actors, Institutions and the Dynamics of Multi-Level Interaction [PDF]
Involvement in EU-sponsored programmes has provided urban institutions and actors across Europe with unprecedented access to new sources of information, legitimacy, and not least, financial support.
Marshall, Adam Jay., Adam Jay Marshall
core
[Extract] One aspect of governance and regulation that tends to be persistently overlooked is the role of private actors, particularly as standard-setting agencies.
Lockie, Stewart +3 more
core +1 more source
COMBINING MULTI-LEVEL AND NETWORK GOVERNANCE WITH A SPILLOVER EFFECT: THE CASE OF THE EUROPEAN “INNOVATION UNION” FLAGSHIP INITIATIVE [PDF]
The purpose of this paper is to demonstrate the possibility of a theoretical up-grade to the framework offered by the theory of governance: from a middle-range theory to a full theory through adding a neofunctionalist component that would enhance its ...
OANA-ANDREEA ION, IOANA DODI, ANDRA POPA
doaj
Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina +11 more
wiley +1 more source
"Modes of governance in the EU" [PDF]
...it is the aim of this chapter to, first, clarify the concept of governance, second, highlight basic modes of governance and their role in the EU and, third, develop an explanatory framework for the emergence of specific modes of governance in the ...
Tömmel, Ingeborg.
core

