Results 31 to 40 of about 12,444,642 (294)
Observations on Multi-level Governance and democracy
Australian and New Zealand Journal of European StudiesThe concept of Multi-level Governance (MLG) emerged in the early 1990s to describe policy-making in the European Union (EU) in the context of enlargement and integration.
Maren Klein, Perparim Xhaferi
doaj +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Transylvanian Review of Administrative Sciences, 2017 Over the past two decades, the concept ofmulti-level governance (MLG) has been increasinglydiscussed by scholars in the fi eld of Europeanintegration.
Vratislav HAVLÍK, Petra KUCHYŇKOVÁ
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Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
EU Transport Infrastructure Policy, New Institutionalism and Types of Multi-Level Governance: The Case of Vienna [PDF]
, 2009 Multi-level Governance (MLG) fundamentally challenges a state-centric, intergovernmentalist understanding of EU policy-making, emphasising the nonhierarchical, interconnected and multi-actor nature of contemporary governing.
Awesti, Anil
core
, 2018 Important policy problems rarely fit neatly within existing territorial boundaries. More difficult still, individual governments or government departments rarely enjoy the power, resources and governance structures required to respond effectively to ...
core +3 more sources
Multi-level governance application to a shared river basin
RBRH, 2020 Water governance systems must be effective in establishing policies capable of guiding decision making. Their framework needs to weigh the intrinsic complexity of inter-scale and multi-level interactions.
Wanessa Dunga de Assis +2 more
doaj +1 more source
Theoretical aspects in multi-level security management of the European Union in the framework of Security Sector Reform (SSR) [PDF]
Przegląd Europejski, 2020 Governance is a way for society to get organised, take and implement decisions by means of mutual understanding, reaching agreements and taking actions. It works at every level and is visible in social, political and economic dimensions.
Luiza Wojnicz
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source