Results 41 to 50 of about 159,405 (302)

Governance system construction for China’s metropolitan regions based on rescaling and multi-level governance: A case study of the Nanjing Metropolitan Region [PDF]

open access: yesZiyuan Kexue
[Objective] Exploring the construction logic of China’s metropolitan regions governance system is conducive to enriching and deepening the research of “city-region” governance mechanism, and providing a scientific basis for promoting the optimisation of ...
YU Jie, LI Luqi, LV Ligang, ZHU Junjun, ZHAO Wei, CHEN Pinyu
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Governance and the Commons in a Multi-Level World

open access: yesInternational Journal of the Commons, 2007
Multi-level governance may facilitate learning and adaptation in complex social-ecological circumstances. Such arrangements should connect community-based management with regional/national government-level management, link scientific management and ...
Derek Armitage
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Conceptual approaches and features of multi-level governance in eu countries: experience for Ukraine

open access: yesTheory and Practice of Public Administration
The article analyzes the conceptual approaches and features of multilevel governance. The main attention is focused on the applied aspects of multilevel governance based on the experience of EU countries, as well as identifying opportunities for its ...
Valentyn Suvorov
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Rethinking Federalism:Network Governance, Multi-Level Governance and Australian Politics

open access: yes, 2017
There has been an explosion of interest in governance and multi-level governance (MLG) over the past 20 years. The literature on governance has drawn attention to the use of networked, collaborative and partnership-based approaches, whilst the concept of
Paul Fawcett   +3 more
core   +1 more source

Levels, scales, linkages, and other 'multiples' affecting natural resources

open access: yesInternational Journal of the Commons, 2012
Natural resources are affected by several types of “multiples.” Some analysts emphasize linkages across multiple scales while others focus on interactions across multi-level institutions or multiple fields of action.
Amy R. Poteete
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

European social dialogue as multi-level governance : towards more autonomy and new dependencies [PDF]

open access: yes, 2012
Almost twenty years ago the Maastricht Treaty introduced procedures for European Social Dialogue, as part of a larger package of measures to strengthen the social dimension of European integration.
Keune, M.; id_orcid   +4 more
core   +1 more source

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