Results 51 to 60 of about 159,405 (302)
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Position of OLAF in a multi-level governance system of the European Union [PDF]
Przegląd Europejski, 2019 The author aims to investigate the position of OLAF in the multi-level governance system (MLG) of the European Union with specific inter-institutional consequences of such location, assuming that OLAF is not a classical supranational institution.
Janusz Ruszkowski
doaj +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
The Application of the multi-level governance model outside the EU-context - the case of food security. EDAP 1/2011 [PDF]
, 2011 The problem of food security governance is systematically gaining in importance but at the same time constitutes one of the less researched areas within the global governance debate.
Marzeda-Mlynarska, Katarzyna.
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The Multi-Level Governance of Intra EU Movement
, 2018 Free movement management is a challenge that emerged in a multi-level context, with policies developed at one level having unclear implications for actors working at other levels, and with questions of authority and competencies remaining highly ...
Zelano, Karin, +7 more
core +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Multi-level Governance in Environmental Risk Management
Oñati Socio-Legal Series, 2013 The article examines regulatory strategies in the field of ecological disaster management with reference to the sociology of risk. The risk perspective draws attention to the fact that political strategies of regulation are to be understood as processes ...
Petra Hiller
doaj
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Developing forest-sector and REDD+ governance: a multi-stage, multi-level and multi-stakeholder approach in Nepal [PDF]
, 2014 This article focuses on the governance of forest carbon emissions projects and policies. It explores how the development of standards through multi-stage, multilevel and multi-stakeholder processes can contribute to ensuring good governance.
Cadman, Tim +2 more
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