Results 81 to 90 of about 2,361,025 (277)

A theory-based decision support framework for energy transition: pluralized perspective

open access: yesFrontiers in Sustainability
This study presents a theory-based decision support framework for energy transitions that addressed the requirement for comprehensive approach beyond routine problem-solving techniques.
Olaoluwa Paul Aasa   +3 more
doaj   +1 more source

Combining nested markets and the multilevel perspective to understand the agroecological transition of the food system [PDF]

open access: yes, 2018
A twofold framework based on nested markets and the multi-level perspective on sustainable transitions is presented. We argue that there are promising intersections between these interrelated concepts, which are useful to understand the emerging dynamics
Cerdan, Claire   +3 more
core  

Strength through diversity: how cancers thrive when clones cooperate

open access: yesMolecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken   +3 more
wiley   +1 more source

Toward system innovation for more sustainable chemistry: insights into consumers’ perceptions, knowledge, and behavior related to traceability and product design strategies along leather supply chains

open access: yesFrontiers in Sustainability
The leather industry is a complex system with multiple actors that faces a fundamental transition toward more sustainable chemistry. To support this process, this article analyzes challenges of the industry and consumers’ roles as a nexus of transition ...
Charis Eisen   +8 more
doaj   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

Transition Processes in Technological Systems: Inspiration from Processes in Biological Evolution

open access: yesBiomimetics
With environmental challenges intensifying, a fundamental understanding and sustainable management of ongoing transition processes are crucial. Biological evolution provides valuable lessons on how to adapt and thrive under changing conditions.
Martin Möller   +3 more
doaj   +1 more source

Multi level perspectives in stock price forecasting: ICE2DE-MDL

open access: yesPeerJ Computer Science
This study proposes a novel hybrid model, called ICE2DE-MDL, integrating secondary decomposition, entropy, machine and deep learning methods to predict a stock closing price. In this context, first of all, the noise contained in the financial time series was eliminated.
Zinnet Duygu Akşehir, Erdal Kılıç
openaire   +3 more sources

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Innovation in the Agro-Food Sector: From technical Innovation-centred Approaches to Sustainability transition Processes [PDF]

open access: yesInternational Journal of Agricultural Management and Development, 2018
Innovation is a complex phenomenon and process involving translation of knowledge into new techniques, products, services. It is considered crucial for sustainable agriculture development and achievement of long-term food security.
Hamid El Bilali
doaj  

Dynamic Multi-Agent Based Variety Formation and Steering in Mass Customization [PDF]

open access: yes
Large product variety in mass customization involves a high internal complexity level inside a company’s operations, as well as a high external complexity level from a customer’s perspective.
Abdelkafi, Nizar   +3 more
core   +1 more source

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