Results 31 to 40 of about 29,068 (302)

Multi item inventory model include lead time with demand dependent production cost and set-up-cost in fuzzy environment [PDF]

Journal of Fuzzy Extension and Applications, 2020
In this paper, we have developed the multi-item inventory model in the fuzzy environment. Here we considered the demand rate is constant and production cost is dependent on the demand rate.
Satya Das
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Goal programming associated with the non-archimedean infinitesimal: a case study applied in the agricultural sector

Production, 2021
Paper aims This work presents a multi-objective method based on goal programming associated with non-Archimedean infinitesimal (NAI) (Improved Weighted Goal Programming method, input-oriented IWGP-MCDEA-BCC).
Fabiana Gomes dos Passos, Ademar Nogueira Nascimento, Cristiano Hora de Oliveira Fontes   +2 more
doaj   +1 more source

Multi-objective optimization techniques in electricity generation planning [PDF]

, 2011
The objective of this research is to develop a framework of multi-objective optimization (MOO) models that are better capable of providing decision support on future long-term electricity generation planning (EGP), in the context of insufficient ...
Tuyiragize, Richard, Richard Tuyiragize
core  

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Linking objective and subjective modeling in engineering design through arc-elastic dominance [PDF]

, 2012
Engineering design in mechanics is a complex activity taking into account both objective modeling processes derived from physical analysis and designers’ subjective reasoning.
LEDOUX, Yann, Sebastian, P., PAILHES, Jerome, SEBASTIAN, Patrick, COLLIGNAN, Arnaud, Collignan, A., Pailhes, J., Ledoux, Y.   +7 more
core   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Robust Integrated Optimization for Green Closed Loop Supply Chain [PDF]

چشم‌انداز مدیریت صنعتی, 2019
With increasing environmental pollution in recent years, researchers have focused on designing a closed loop supply chain network with consideration of environmental issues.
Saba Manouchehri, Ali Tajdin, Babak Shirazi   +2 more
doaj   +1 more source

Design optimization of multi energy systems for domestic hot water uses on the building sector

Green Energy and Sustainability, 2021
The burden that has come upon the environment, combined with the ever-declining fossil fuel reserves, has led to the need of reducing the conventional energy consumption in building sector and to the promotion of systems based on Renewable Energy Sources
Vasileios Kilis, Nikolaos Ploskas, Giorgos Panaras   +2 more
doaj   +1 more source