Results 41 to 50 of about 397,584 (291)

Continuous multi-criteria methods for crop and soil conservation planning on La Colacha (Río Cuarto, Province of Cordoba, Argentina) [PDF]

open access: yes, 2012
Agro-areas of Arroyos Menores (La Colacha) west and south of Rand south of R?o Cuarto (Prov. of Cordoba, Argentina) basins are very fertile but have high soil loses.
Aguado Cortijo, Pedro Luis   +7 more
core   +2 more sources

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

Robust Integrated Optimization for Green Closed Loop Supply Chain [PDF]

open access: yesچشم‌انداز مدیریت صنعتی, 2019
With increasing environmental pollution in recent years, researchers have focused on designing a closed loop supply chain network with consideration of environmental issues.
Saba Manouchehri   +2 more
doaj   +1 more source

Design optimization of multi energy systems for domestic hot water uses on the building sector

open access: yesGreen Energy and Sustainability, 2021
The burden that has come upon the environment, combined with the ever-declining fossil fuel reserves, has led to the need of reducing the conventional energy consumption in building sector and to the promotion of systems based on Renewable Energy Sources
Vasileios Kilis   +2 more
doaj   +1 more source

Scalable Design Space Exploration via Answer Set Programming [PDF]

open access: yes, 2016
The design of embedded systems is becoming continuously more complex such that the application of efficient high level design methods are crucial for competitive results regarding design time and performance.
Wanko, Philipp
core   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

Fuzzy Programming for Multi-choice Bilevel Transportation Problem [PDF]

open access: yesOperations Research and Decisions, 2021
Multi-choice programming problems arise due to the diverse needs of people. In this paper, multi-choice optimization has been applied to the bileve transportation problem. This problem deals with transportation at both the levels, uppe r as well as lower.
Ritu Arora, Kavita Gupta
doaj  

A goal programming methodology for multiobjective optimization of distributed energy hubs operation [PDF]

open access: yes, 2014
This paper addresses the problem of optimal energy flow management in multicarrier energy networks in the presence of interconnected energy hubs. The overall problem is here formalized by a nonlinear constrained multiobjective optimization problem and ...
A. Vaccaro   +16 more
core   +2 more sources

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

open access: yesAging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef   +2 more
wiley   +1 more source

A Systematic Comparison of Alpha‐Synuclein Seed Amplification Assays for Increasing Reproducibility

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Seed amplification assays (SAAs) enable ultrasensitive detection of misfolded α‐synuclein across biofluids and tissues. Yet, heterogeneity in protocols limits cross‐study comparability and clinical translation. Here, we review α‐synuclein SAA methods and their performance across various biological matrices.
Manuela Amaral‐do‐Nascimento   +3 more
wiley   +1 more source

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