Results 41 to 50 of about 12,816,466 (238)

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Elite Multi-Criteria Decision Making—Pareto Front Optimization in Multi-Objective Optimization

Algorithms
Optimization is a process of minimizing or maximizing a given objective function under specified constraints. In multi-objective optimization (MOO), multiple conflicting functions are optimized within defined criteria.
Adarsh Kesireddy, F. Antonio Medrano
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Multi-Objective Planning of Distributed Photovoltaic Power Generation Based on Multi-Attribute Decision Making Theory

IEEE Access, 2020
Photovoltaic (PV) power generation has been heavily connected into distribution network recently. However, the intermittent and uncertainty of PV generation system will significantly affect the security operation of distribution network.
Changchun Cai, Jie Chen, Mengrui Xi, Yuan Tao, Zhixiang Deng   +4 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Multi-objective decision making

, 2017
Many real-world decision problems have multiple objectives. For example, when choosing a medical treatment plan, we want to maximize the efficacy of the treatment, but also minimize the side effects.
Shimon Whiteson, Whiteson, Shimon, Roijers, DM, Whiteson, S, Diederik M. Roijers   +4 more
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

A BI-LEVEL LINEAR MULTI-OBJECTIVE DECISION MAKING MODEL WITH INTERVAL COEFFICIENTS FOR SUPPLY CHAIN COORDINATION

International Journal of Industrial Engineering and Production Research, 2008
Bi-level programming, a tool for modeling decentralized decisions, consists of the objective(s) of the leader at its first level and that is of the follower at the second level.
M.B. Aryanezhad, E. M.B.Aryanezhad & E.Roghanian   +1 more
doaj   +2 more sources

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Multi-objective data envelopment analysis: A game of multiple attribute decision-making

Journal of Economics and Management, 2019
Aim/purpose ‒ The traditional data envelopment analysis (DEA) is popularly used to evaluate the relative efficiency among public or private firms by maximising each firm’s efficiency: the decision maker only considers one decision-making unit (DMU) at ...
Chen Yuh Wen
doaj   +1 more source