Alternative rational technique to compute multi-objective linear programming problems [PDF]
In this paper, we have been suggested an alterative rational technique to compute the value of the objective function of a multi-objective linear programming problems. Numerical results indicate that the efficiency of our proposed technique corresponding
Abbas al-Bayati +2 more
doaj +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Fuzzy rough bi-level multi-objective nonlinear programming problems
Fuzzy rough bi-level multi-objective nonlinear programming problem (FRBMNPP) moved toward becoming rise normally in various real applications. In this article we develop bi-level multi-objective nonlinear programming problem (BMNPP), in which the ...
M.A. Elsisy, M.A. El Sayed
doaj +1 more source
An evolutionary programming algorithm for multi-objective optimisation [PDF]
This paper describes a new evolutionary programming optimisation algorithm and a method of its application to multi-objective optimization problems. Computational results are presented demonstrating the algorithm's ability to find Pareto-optimal solutions for a real-world problem in radio frequency component design.
Andrew Lewis 0004, David Abramson 0001
openaire +2 more sources
Construction of image feature extractors based on multi-objective genetic programming with redundancy regulations [PDF]
This paper proposes a multi-objective genetic programming (MOGP) for automatic construction of feature extraction programs (FEPs). The proposed method is modified from a well known non-dominated sorting evolutionary algorithm, i.e., NSGA-II.
Hiroaki Kudo +9 more
core +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Hybrid behavioural-based multi-objective space trajectory optimization [PDF]
In this chapter we present a hybridization of a stochastic based search approach for multi-objective optimization with a deterministic domain decomposition of the solution space.
Vasile, Massimiliano
core +5 more sources
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source

