Results 61 to 70 of about 572,594 (291)

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Multi-Objective Optimization for Power Efficient Full-Duplex Wireless Communication Systems

open access: yes, 2015
In this paper, we investigate power efficient resource allocation algorithm design for multiuser wireless communication systems employing a full-duplex (FD) radio base station for serving multiple half-duplex (HD) downlink and uplink users simultaneously.
Ng, Derrick Wing Kwan   +2 more
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Multi-objective probabilistic fractional programming problem involving two parameters Cauchy distribution

open access: yesMathematical Modelling and Analysis, 2019
The paper presents the solution methodology of a multi-objective probabilistic fractional programming problem, where the parameters of the right hand side constraints follow Cauchy distribution. The proposed mathematical model can not be solved directly.
Srikumar Acharya   +2 more
doaj   +1 more source

Multi-objective techniques in genetic programming for evolving classifier systems [PDF]

open access: yes, 2005
The application of multi-objective evolutionary computation techniques to the genetic programming of classifiers has the potential to both improve the accuracy and decrease the training time of the classifiers.The performance of two such algorithms are ...
Ciesielski, V, Li, X, Parrott, D
core  

Learning Optimal Control of Synchronization in Networks of Coupled Oscillators using Genetic Programming-based Symbolic Regression

open access: yes, 2017
Networks of coupled dynamical systems provide a powerful way to model systems with enormously complex dynamics, such as the human brain. Control of synchronization in such networked systems has far reaching applications in many domains, including ...
Abel, Markus   +4 more
core   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

A Synthesizing Effect-Based Solution Method for Stochastic Rough Multi-objective Programming Problems [PDF]

open access: yesInternational Journal of Computational Intelligence Systems, 2014
Multi-objective programming with uncertain information has been widely applied in modeling of industrial produce and logistic distribution problems. Usually the expectation value model and chance-constrained model as solution models are used to deal with
Lei Zhou, Guoshan Zhang, Fachao Li
doaj   +1 more source

On Singular Control Problems with State Constraints and Regime-Switching: A Viscosity Solution Approach

open access: yes, 2014
This paper investigates a singular stochastic control problem for a multi-dimensional regime-switching diffusion process confined in an unbounded domain.
Alvarez   +24 more
core   +1 more source

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