Results 71 to 80 of about 572,594 (291)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

DEA common set of weights based on a multi objective Fractional Programming

International Journal of Industrial Engineering and Production Research, 2014
Data envelopment analysis operates as a tool for appraising the relative efficiency of a set of homogenous decision making units. This methodology is applied widely in different contexts.
Seyed Hossein Razavi Hajiagha, Shide Sadat Hashemi, Hannan Amoozad Mahdiraji   +2 more
doaj  

A MOLFP Method for Solving Linear Fractional Programming Under Fuzzy Environment [PDF]

International Journal of Research in Industrial Engineering, 2017
In this paper, a solution procedure is proposed to solve Fully Fuzzy Linear Fractional Programming (FFLFP) problem where all the variables and parameters are triangular fuzzy numbers.
S.K. Das, T. Mandal
doaj   +1 more source

Multi-Objective region-Aware optimization of parallel programs [PDF]

Parallel Computing, 2019
Auto-tuning has become increasingly popular for optimizing non-functional parameters of parallel programs. The typically large search space requires sophisticated techniques to find well-performing parameter values in a reasonable amount of time. Different parts of a program often perform best with different parameter values.
Durillo, Juan J., Gschwandtner, Philipp, Kofler, Klaus, Fahringer, Thomas   +3 more
openaire   +2 more sources

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

A Two-Stage Multi-objective Programming Model to Improve the Reliability of Solution

International Journal of Computational Intelligence Systems, 2020
Randomness is a common uncertainty encountered in practical multi-objectives decision-making. But it is always a challenge for decision-makers to process randomness in multi-objective programming problems.
Chenxia Jin, Fachao Li, Kaixin Feng, Yunfeng Guo   +3 more
doaj   +1 more source

Multi-Objective Gene Expression Programming for Clustering

Information Technology And Control, 2012
This paper proposes a multi-objective gene expression programming for clustering (MGEPC), which could automatically determine the number of clusters and the appropriate partitioning from the data set. The clustering algebraic operations of gene expression programming are extended first.
Yifei Zheng, Lixin Jia, Hui Cao 0003
openaire   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

A pythagorean hesitant fuzzy programming approach and its application to multi objective reliability optimization problem [PDF]

Yugoslav Journal of Operations Research
Decision-making problems can often be effectively solved using traditional optimization methods that have a clearly defined configuration. However, in real-world scenarios, decision-makers frequently encounter doubt or hesitation, making it challenging ...
Jana Swarup, Islam Sahidul
doaj   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source