Results 51 to 60 of about 8,593,463 (294)

Designing a Multi-objective Stochastic programming model for portfolio selection [PDF]

open access: yesمدیریت صنعتی, 2015
In traditional portfolio selection model coefficients often are certain and deterministic, but in real world these coefficients are probabilistic. So decision maker cannot estimate them exactly.
Alireza Sharifisalim   +3 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

On Solving Fully Rough Multi-Objective Integer Linear Programming Problems [PDF]

open access: yesDelta Journal of Science, 2019
In this paper a suggested algorithm to solve fully rough multi-objectiveinteger linear programming problem [FRMOILP] is described. In orderto solve this problem and find rough value efficient solutions anddecision rough integer variables by the slice-sum
Abdusalam Emsimir, El-Saeed Ammar
doaj   +1 more source

A Multi-Level Multi-Objective Integer Quadratic Programming Problem Under Pentagonal Neutrosophic Environment

open access: yesFuzzy Information and Engineering, 2023
The aim of this paper is to propose an algorithm to solve and enhance a multi-level multi-objective integer quadratic programming problem (MLMOIQPP) under a single-valued Pentagonal Neutrosophic environment applied to the objective functions.
N. M. Bekhit   +2 more
doaj   +1 more source

On generalised convex multi-objective nonsmooth programming [PDF]

open access: yesThe Journal of the Australian Mathematical Society. Series B. Applied Mathematics, 1996
AbstractWe extend the concept of V-pseudo-invexity and V-quasi-invexity of multi-objective programming to the case of nonsmooth multi-objective programming problems. The generalised subgradient Kuhn-Tucker conditions are shown to be sufficient for a weak minimum of a multi-objective programming problem under certain assumptions.
Mishra, S. K., Mukherjee, R. N.
openaire   +1 more source

Recombination and Self-Adaptation in Multi-objective Genetic Algorithms [PDF]

open access: yes, 2004
This paper investigates the influence of recombination and self-adaptation in real-encoded Multi-Objective Genetic Algorithms (MOGAs). NSGA-II and SPEA2 are used as example to characterize the efficiency of MOGAs in relation to various recombination ...
Régnier, Jérémi   +5 more
core   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Modeling Multi-Objective, Multi-Product and Multi-Period Supplier Selection Problem Considering Stochastic Demand [PDF]

open access: yesمدیریت تولید و عملیات, 2018
In this paper, a multi-objective, multi-period and multi-product mixed integer programming model ‎for the supplier selection and quota allocation problem under an all-unit quantity discount policy, ‎constrained storage space and stochastic demand is ...
Mehdi Seifbarghy, Foruzan Naseri
doaj   +1 more source

Multi-objective optimisation for receiver operating characteristic analysis [PDF]

open access: yes, 2013
Copyright © 2006 Springer-Verlag Berlin Heidelberg. The final publication is available at link.springer.comSummary Receiver operating characteristic (ROC) analysis is now a standard tool for the comparison of binary classifiers and the selection ...
Richard M. Everson   +3 more
core   +1 more source

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