Results 51 to 60 of about 132,617 (313)
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
An Interactive Fuzzy Satisficing Method for Fuzzy Random Multiobjective 0-1 Programming Problems through Probability Maximization Using Possibility [PDF]
, 2009 In this paper, we focus on multiobjective 0-1 programming problems under the situation where stochastic uncertainty and vagueness exist at the same time.
Matsui, Takeshi +3 more
core
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Fuzzy Information and Engineering, 2023 The aim of this paper is to propose an algorithm to solve and enhance a multi-level multi-objective integer quadratic programming problem (MLMOIQPP) under a single-valued Pentagonal Neutrosophic environment applied to the objective functions.
N. M. Bekhit +2 more
doaj +1 more source
An evolutionary programming algorithm for multi-objective optimisation [PDF]
The 2003 Congress on Evolutionary Computation, 2003. CEC '03., 2004 This paper describes a new evolutionary programming optimisation algorithm and a method of its application to multi-objective optimization problems. Computational results are presented demonstrating the algorithm's ability to find Pareto-optimal solutions for a real-world problem in radio frequency component design.
Andrew Lewis 0004, David Abramson 0001
openaire +2 more sources
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
A Tutorial on Evolutionary Multi-Objective Optimization (EMO) [PDF]
, 2005 Many real-world search and optimization problems are naturally posed as non-linear programming problems having multiple objectives. Due to lack of suitable solution techniques, such problems are artificially converted into a single-objective problem
Deb, Kalyanmoy
core +1 more source
On the Use of Semantics in Multi-objective Genetic Programming [PDF]
, 2016 Research on semantics in Genetic Programming (GP) has increased dramatically over the last number of years. Results in this area clearly indicate that its use in GP can considerably increase GP performance. Motivated by these results, this paper investigates for the first time the use of Semantics in Muti-Objective GP, within the well-known NSGA-II ...
Galván-López, Edgar +3 more
openaire +2 more sources
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Maximizing energy-efficiency in multi-relay OFDMA cellular networks [PDF]
, 2013 This contribution presents a method of obtaining the optimal power and subcarrier allocations that maximize the energy-efficiency (EE) of a multi-user, multi-relay, orthogonal frequency division multiple access (OFDMA) cellular network.
Cheung, Kent Tsz Kan +5 more
core +1 more source