Results 51 to 60 of about 212,366 (287)

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Deep Coal Rock Gas Reservoir Inversion Prediction Method Based on Multi Quality Parameter Coupling

Cejing jishu
As a new type of unconventional natural gas resources, deep coal rock gas has become a hot spot for exploration in major oil and gas fields in China. However, it is different from conventional shallow coalbed methane. Adsorbed gas and free gas coexist in
MAO Chenfei, ZHANG Xiao, ZHANG Wenqian, ZHANG Ben, CHEN Guojun, GAO Ming, YONG Lin, HUANG Ping   +7 more
doaj   +1 more source

Inversion of Rayleigh wave dispersion curves based on antlion optimizer

地质科技通报, 2023
Inverting Rayleigh wave dispersion curves to obtain S-wave velocity profiles is one of the most important steps in near-surface Rayleigh wave exploration.
Yiming Wang, Xianhai Song, Xueqiang Zhang   +2 more
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Oilfield Reservoir Parameter Inversion Based on 2D Ground Deformation Measurements Acquired by a Time-Series MSBAS-InSAR Method

Remote Sensing, 2023
Time-series ground deformation monitoring and reservoir parameter inversion are crucial for the dynamic assessment of oilfield resources and sustainable exploitation in oilfields.
Anmengyun Liu, Rui Zhang, Yunjie Yang, Tianyu Wang, Ting Wang, Age Shama, Runqing Zhan, Xin Bao   +7 more
doaj   +1 more source

Development of a Prediction Model for Progression Risk in High‐Grade Gliomas Based on Habitat Radiomics and Pathomics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate the value of constructing models based on habitat radiomics and pathomics for predicting the risk of progression in high‐grade gliomas. Methods This study conducted a retrospective analysis of preoperative magnetic resonance (MR) images and pathological sections from 72 patients diagnosed with high‐grade gliomas (52 ...
Yuchen Zhu, Yuxi Gong, Weilin Xu, Xingjian Sun, Gefei Jiang, Lei Qiu, Kexin Shi, Mengxing Wu, Yinjiao Fei, Jinling Yuan, Jinyan Luo, Yurong Li, Yuandong Cao, Minhong Pan, Shu Zhou   +14 more
wiley   +1 more source

Linear Precoding for Broadcast Channels with Confidential Messages under Transmit-Side Channel Correlation

, 2013
In this paper, we analyze the performance of regularized channel inversion (RCI) precoding in multiple-input single-output (MISO) broadcast channels with confidential messages under transmit-side channel correlation.
Al-nahari, Azzam Y., Collings, Iain B., Geraci, Giovanni, Yuan, Jinhong   +3 more
core   +1 more source

Diffusion Spectrum Imaging Maps Early Axonal Loss and a Unique Progressive Signal in Neuronal Intranuclear Inclusion Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang, Yixiu Pei, Xiaobao Hu, Ying Xiong, Fang Wang, Yanyan Yu, Min Zhu, Dandan Tan, Meihong Zhou, Daojun Hong, Fuqing Zhou   +10 more
wiley   +1 more source

Study on the Multi-parameter Inversion of Reservoir Water Quality Based on GF-1 WFV Image and Neural Network Model

Renmin Zhujiang, 2020
This paper establishes a multi-parameter quantitative inversion model of water qualityin multispectral remote sensing images by domestic GF-1 WFV image and neural network model toachieve high-efficiency, large-scale, continuous-space and multi-parameter ...
ZHENG Yanhui, ZHANG Yuanbo, HE Yanhu
doaj  

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators   +26 more
wiley   +1 more source