Results 71 to 80 of about 5,551,543 (292)
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Pendulums and Nonlinear Effects - Warning 4000 level physics [video]
, 2015 NPS PhysicsIn-class Physics DemonstrationsDr.
Naval Postgraduate School Physics
core +1 more source
Tailoring the slow light behavior in terahertz metasurfaces [PDF]
, 2015 10.1063/1.4919531Applied Physics ...
Zhang, Weili +13 more
core +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Versatile vector tools for efficient protein screening across multiple expression systems
FEBS Open Bio, EarlyView.A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu +5 more
wiley +1 more source
Ferroelectric critical size of SnTe nanoribbon and its mechanical strain engineering
Nihon Kikai Gakkai ronbunshu, 2020 We investigate the critical size of ferroelectricity in monolayer tin telluride (SnTe) nanoribbon by using ab initio (first-principles) density functional theory calculations.
Koichiro MINAGURO +3 more
doaj +1 more source
Understanding vacuum arc ignition by concurrent multi-physics simulations
, 2023 Vacuum arcs have been studied intensively for more than a century. Yet, the physical mechanisms involved in their ignition remain unclear, mainly due to the extreme nature and high complexity of the physical processes involved.
Djurabekova, Flyura +5 more
core +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Multi-physics coupling simulation in virtual reactors
SIMULATION, 2019 Nuclear power stations involve a range of complex and interacting multi-physical processes. With the rapid development of high-performance computing technology, accurate multi-physics simulation in virtual reactors has drawn more and more attention in industry and academia.
Xianmeng Wang +6 more
openaire +1 more source
FEBS Open Bio, EarlyView.We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen +5 more
wiley +1 more source